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Mario A. Di Pascuale, H D. Cavanagh; Analysis Of Dsaek Dislocation Rate By: Graft Thickness, Graft Size, Preoperative Storage Time, And Endothelial Cell Count. Invest. Ophthalmol. Vis. Sci. 2011;52(14):747.
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A clear cornea is a pre-requisite for normal vision. Recent surgical techniques of are aimed to replaced only the affected corneal layer, either the anterior or the posterior layers. These surgical techniques such as Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) has emerged for patients with corneal endothelial cell dysfunction; herein we will analyze the factors associated in DSAEK graft dislocation rate such as graft dislocation, preoperative storage time and endothelial cell count.
We reviewed retrospective the last 5 years period time in cases of corneal endothelial cell dysfunction who underwent to DSAEK. We studied the pre-operative corneal donor data including pre-operative storage time and endothelial cell count as well as, surgical technique employed, corneal incision size and post-operative graft thickness, graft size. This analysis will be carried on between pre-operative time to 1 year after surgery.
In the last 5 years, we found a dislocation rate of 25%. The central corneal thickness during the last visit was 668.7±99.8 µm (P< 0.0001), the mean grafts size was 8.3±0.5 mm, the mean preoperative endothelial cells count in the grafts was 2533±190 cell/mm and the mean preoperative storage time was 5.2±3 . There was no statistically significant correlation among graft dislocation and CCT, graft size, preoperative storage time and endothelial cell count.
This retrospective study revealed that graft thickness, graft size, preoperative storage time and preoperative endothelial cells count were not associated with increased graft dislocation after DSAEK.
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