April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Investigation Of The Mechanism Of Near-infrared Induced Cataract
Author Affiliations & Notes
  • Masami Kojima
    Vis Res for Environmtl Hlth/Med Res Inst, Kanazawa Med Univ, Kahoku, Japan
  • Sachiko Yamaguchi
    Division of Health Effects Research, Japan National Institute of Occupational Safety and Health, Kawasaki, Japan
  • Tsutomu Okuno
    Division of Health Effects Research, Japan National Institute of Occupational Safety and Health, Kawasaki, Japan
  • Yoshihisa Ishiba
    Vision caring and optical laboratory, Yamamoto Kogaku, CO, LTD., Kahoku, Japan
  • Kazuyuki Sasaki
    Div of Vis Rsrch for Environ Hlth, Kanazawa Medical University, Uchinada, Japan
    Department of Rehabilitation, Tohoku Bunka Gakuin, Sendai, Japan
  • Hiroshi Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, Japan
  • Footnotes
    Commercial Relationships  Masami Kojima, None; Sachiko Yamaguchi, None; Tsutomu Okuno, None; Yoshihisa Ishiba, Yamamoto Kogaku, CO, LTD. (E); Kazuyuki Sasaki, None; Hiroshi Sasaki, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 798. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Masami Kojima, Sachiko Yamaguchi, Tsutomu Okuno, Yoshihisa Ishiba, Kazuyuki Sasaki, Hiroshi Sasaki; Investigation Of The Mechanism Of Near-infrared Induced Cataract. Invest. Ophthalmol. Vis. Sci. 2011;52(14):798.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose: : This study examines the mechanism of near-infrared, namely infrared A (IRA), light induced cataract.

Methods: : Near infrared (wavelength 808 nm; power 0.6 W; exposed area 6 mm diameter) was exposed to the vicinity of the boundary of the iris and pupil of 6 rabbits eyes for six minutes (The part around the crystalline lens attained thermal equilibrium under this exposure in the preliminary experiment). We checked the ocular condition before and after exposure by slit-lamp. After injection of 0.2% aqueous solution of microencapsulated liquid crystal (MTLC changes color through red, yellow, green and blue with temperature elevation) into the anterior chamber of a second rabbit group, infrared (power 0.2 W; exposed area 6 mm diameter) was again exposed. Temperature distribution in the anterior chamber under the exposure was measured.

Results: : Myosis by iridocyclitis, discoloration of iris and iris atrophy were observed from immediately after exposure in the area under exposure. One day after exposure, posterior synechia of the iris and cortical cataract were seen in the exposed area. Lens opacity of the pupillary zone was very light. No ocular change was seen in non-exposed control eyes. The first temperature changes in the anterior chamber of IRA exposed eyes were observed to the right above the iris where the temperature reached over 40ºC.

Conclusions: : The mechanism of infrared induced cataract was that IRA absorbed by the iris and pupil generated heat. This heat was secondarily transported to the lens and induced cataract.

Keywords: cataract • radiation damage: light/UV • laser 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.