April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Elastic Properties Of Human Lens Zonules In Presbyopic Donor Eyes As A Function Of Age
Author Affiliations & Notes
  • Marek Mikielewicz
    Instituto Barraquer, Barcelona, Spain
  • Carlos H. Gordillo
    Instituto Barraquer, Barcelona, Spain
  • Gustavo A. Montenegro
    Instituto Barraquer, Barcelona, Spain
  • Rafael I. Barraquer
    Instituto Barraquer, Barcelona, Spain
  • Ralph Michael
    Instituto Barraquer, Barcelona, Spain
  • Footnotes
    Commercial Relationships  Marek Mikielewicz, None; Carlos H. Gordillo, None; Gustavo A. Montenegro, None; Rafael I. Barraquer, None; Ralph Michael, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 817. doi:
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      Marek Mikielewicz, Carlos H. Gordillo, Gustavo A. Montenegro, Rafael I. Barraquer, Ralph Michael; Elastic Properties Of Human Lens Zonules In Presbyopic Donor Eyes As A Function Of Age. Invest. Ophthalmol. Vis. Sci. 2011;52(14):817.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To measure ex-vivo the stress-strain relationship of the human lens zonules.

Methods: : Eleven presbyopic human donors eyes were classified by age in three groups (median age 60, 73 and 90 years) and measured in a device consisting of a rigid bench for holding and stretching coronal eye sections including the ciliary-lens zone. Radial stretching was created by a stepper motor coupled to a digital outside micrometer for linear displacement and distance measurement, and a digital balance for load measuring.

Results: : Zonular elongation by 200 µm produced a mean load of 4.4; 3.3 and 2.8 mN in the different age groups (60, 73 and 90 years respectively). Increased elongation above physiological limits to 650 µm resulted in a mean load of 9.2; 6.9 and 6.2 mN, respectively. (10 mN = 1.02 g)

Conclusions: : The force needed to stretch the human lens zonules decreases between the age of 60 to 90 years by about 30%.

Keywords: accommodation • aging • presbyopia 

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