Purchase this article with an account.
Takako Hirashima, Kazuaki Nishijima, Tomoaki Murakami, Akihito Uji, Tadamichi Akagi, Takahiro Horii, Naoko Arakawa, Yuuki Muraoka, Abdallah Ellabban, Nagahisa Yoshimura; Retinal Hyperreflective Foci on Optical Coherence Tomography before Vitrectomy for Diabetic Macular Edema and Postoperative Outcomes. Invest. Ophthalmol. Vis. Sci. 2011;52(14):990.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To assess the correlation between retinal hyperreflective foci detected by spectral-domain optical coherence tomography (SD-OCT) before vitrectomy for diabetic macular edema (DME) and visual outcomes after surgery.
We retrospectively reviewed consecutive 76 eyes of 69 patients with DME who were treated with vitrectomy from October 2007 to September 2009. Thirty-two eyes of 28 patients without a thickened or taut posterior hyaloid membrane, who were scanned by SD-OCT before surgery and were followed up for at least 6 months after vitrectomy without any complications, were included in this study. The distribution of retinal hyperreflective foci on SD-OCT before surgery, the macular thickness, and best-corrected visual acuity (BCVA) during follow-up periods were studied.
The mean follow-up period was 15.3 ± 6.1 months. The final BCVA improved in 14 (44%), remained unchanged in 12 eyes (38%), and worsened in 6 eyes (19%). There were no significant differences in postoperative foveal thickness decrease and BCVA improvement between in the cases with rich intraretinal hyperreflective foci and in those with only a few. In the cases with subfoveal hyperreflective foci, improvement in BCVA was significantly limited, although the foveal thickness was significantly reduced after vitrectomy.
Subfoveal hyperreflective foci detected by OCT preoperatively could be a negative factor for the result of vitrectomy against DME.
This PDF is available to Subscribers Only