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Lukas Reznicek, Thomas Klein, Wolfgang Wieser, Christoph M. Eigenwillig, Benjamin Biedermann, Anselm Kampik, Robert Huber, Aljoscha Neubauer; 1.4 Mhz Ultra High-speed Ultra Wide-field Swept Source Oct. Invest. Ophthalmol. Vis. Sci. 2011;52(14):1754.
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To investigate 1.4 MHz ultra high-speed ultra wide-field swept source Fourier domain mode locking (FDML) OCT regarding feasibility and its image quality.
A 1050nm swept source FDML OCT was constructed running at 1.4 MHz A-scan rate, which covers approx. 70° field of view. Imaging of normal eyes was performed with the device using 1900x1900 A-scans in approx. 3 seconds. Image results were compared with Spectralis OCT (Heidelberg Engineering, Germany) image quality of the same eyes.
The images of 11 normal eyes obtained at an A-scan rate of 1.4 MHz covered a wide field of view, including the complete macula and optic disc. The image quality of the raw OCT scans showed reasonable - but lower - quality versus the processed Heidelberg scans. When averaging 5 scans in X-Y direction, an image quality more comparable to Heidelberg scans was obtained at 1.4 MHz, while yielding an orders of magnitude higher number of 3D data points.
3D OCT at 1.4 MHz is feasible by swept source FDML OCT and offers high data density at still reasonable OCT image quality.
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