March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Repeatability Of Retinal Macular Thickness Measurements In Patients With Diabetic Clinically Significant Macular Edema Using Two Different Scanning Protocols Of Spectralis Optical Coherence Tomography
Author Affiliations & Notes
  • Tito Fiore
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Marco Lupidi
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Barbara Iaccheri
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Gianluigi Tosi
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Daniela Fruttini
    Economic, Financial and Statistical, University of Perugia, Perugia, Italy
  • Amedeo Pieri
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Alessia Iannone
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Antonio Garritano
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Carlo Cagini
    Ophthalmology, Eye Clinic, University of Perugia, Perugia, Italy
  • Footnotes
    Commercial Relationships  Tito Fiore, None; Marco Lupidi, None; Barbara Iaccheri, None; Gianluigi Tosi, None; Daniela Fruttini, None; Amedeo Pieri, None; Alessia Iannone, None; Antonio Garritano, None; Carlo Cagini, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 2094. doi:
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      Tito Fiore, Marco Lupidi, Barbara Iaccheri, Gianluigi Tosi, Daniela Fruttini, Amedeo Pieri, Alessia Iannone, Antonio Garritano, Carlo Cagini; Repeatability Of Retinal Macular Thickness Measurements In Patients With Diabetic Clinically Significant Macular Edema Using Two Different Scanning Protocols Of Spectralis Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2094.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the repeatability of OCT Spectralis retinal thickness (RT) measurements in diabetic patients with clinical significant macular edema (CSME) using two different scanning methods.

Methods: : Fifty-four eyes of 54 diabetic patients with CSME were included in the study. Repeatability and intrasession correlation coefficients were tested with 20 x 15 degree raster scans consisting of 19 (group I) or 37 (group II) high-resolution line scans that were repeated two times by 1 experienced examiner.

Results: : In diabetic patients, examining the five ETDRS inner areas, coefficient of repeatability was less than 2% for both group. Moreover, intrasession coefficients of variation for all ETDRS inner areas were less than 0.4% for both scanning protocols. Average ± SD thickness was found 396 ± 104 μm in group I and 390 ± 104 μm in group II. Mean absolute change in thickness ± SD was 0.5 ± 4.4 in group I and 0 ± 2.3 in group II. Mean relative change in thickness was 0.14% in group I and 0.1% in group II. No statistically significant differences were found between obtained measurement in group I and group II.

Conclusions: : RT measurements in diabetic patients with CSME are repeatable using both scanning protocols (19 or 37 B-scans) with OCT Spectralis. The results indicate that a change in central subfield thickness exceeding 11 µm is likely to be real.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • edema • diabetes 
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