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Di Ma, Mingzhi Zhang, Kunliang Qiu, Shibin Lin, Taiping Li; Retinal Nerve Fiber Layer Measurement In Normal Children: A Comparative Study Of Spectral-domain Optical Coherence Tomography And Scanning Laser Polarimetry. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2110.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the retinal nerve fibre layer (RNFL) thickness in children with normal vision by using spectral domain optical coherence tomography (Cirrus HD OCT) and scanning laser polarimetry with enhanced corneal compensator (GDx ECC).
A total of 45 eyes from 45 healthy Chinese children with normal vision (8-17 years) were recruited. The RNFL in each eye was imaged sequentially with the Cirrus OCT and GDx ECC. The relationship between CirrusOCT and GDx ECC RNFL measurements was examined with linear regression analysis.
The mean age, axial length, and spherical equivalent were 12.53± 1.80 years (range, 8-17), 24.62 ±1.10 mm (range, 22.11-27.36mm), and -2.41± 1.80 D (range, 0.25 to -6.38D), respectively. Both Cirrus OCT and GDx ECC showed double hump patterns in the RNFL profiles. The average RNFL thickness was 100.53 +/- 10.56 by Cirrus OCT and 56.42 +/- 6.39 um by GDx ECC. Significant differences were found in the average RNFL thickness between Cirrus OCT and GDx ECC (p<0.01). The average RNFL thickness measured with CirrusOCT and GDx ECC correlated significantly with each other (r = 0.59, p<0.01).
Both Cirrus OCT and GDx ECC showed double hump patterns in the RNFL profiles in normal children. Despite the substantial differences in RNFL thicknesses among the children, significant correlations were observed between CirrusOCT and GDx ECC RNFL measurements, indicating both technologies to be robust.
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