Purpose:
To correlate choroidal and retinal abnormalities in chronic central serous chorioretinopathy.
Methods:
Twelve patients (24 eyes) with chronic central serous chorioretinopathy with no prior treatment underwent indocyanine green angiography (ICGA) and enhanced depth optical coherence tomography (ED-OCT). Choroidal thickness was measured in the fovea. Dilated choroidal veins were identified on ICGA and ED-OCT.
Results:
The mean age of patients was 46 years. Ten patients were male (83%); and seven (58%) had bilateral disease. As compared to a control group, all patients had retrofoveolar choroidal thickening (496 microns), and focal choroidal thickening in the areas of dilated veins (number). ED-OCT analysis in the areas of dilated choroidal veins found an absence of overlying choriocapillaris in 16 eyes, a deformation of Bruch membrane in 12 eyes, and damage to the outer retina in 6 eyes.
Conclusions:
Chronic CRSC is associated with dilated choroidal veins, which frequently colocalize with focal atrophy of the outer retina. This suggests that chronic CSCR may be a venous choroidal disorder with secondary ischemic damage to the retinal pigment epithelium.
Keywords: imaging/image analysis: clinical • choroid • retinal pigment epithelium