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Apurva K. Patel, Gennady Landa, Chavakij Bhoomibunchoo, Nicole Scripsema, James Saunders, Richard B. Rosen; Retinal Blood Flow in Patients with Sickle Cell Retinopathy assessed by Retinal Function Imager. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2156.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate retinal blood flow velocities in patients with sickle cell retinopathy(SCR) by using Retinal Function Imager (RFI).
Fifteen patients with SCR underwent testing with the RFI. A comparison to the values of normal subjects was performed.
In the eyes of patients with sickle cell retinopathy, mean arterial and venous blood flow velocities were measured as 3.07+0.71 mm/sec and 2.12+0.54 mm/sec, respectively. While both arterial and venous velocities were found to be reduced in patients with SCR in comparison to normal subjects, only for retinal venous blood flow velocity there was a statistically significant difference (p=0.115 for arterial and p=0.003 for venous blood flow velocity).
Reduced retinal blood flow may play an important role in the development of sickle cell retinopathy.
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