March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Retinal Blood Flow in Patients with Sickle Cell Retinopathy assessed by Retinal Function Imager
Apurva K. Patel; Gennady Landa; Chavakij Bhoomibunchoo; Nicole Scripsema; James Saunders; Richard B. Rosen
Author Affiliations & Notes
  • Apurva K. Patel
    The Einhorn Clinical Research Center and Bendheim Family Retina Center, Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, New York Medical College, Valhalla, New York
  • Gennady Landa
    The Einhorn Clinical Research Center and Bendheim Family Retina Center, Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, New York Medical College, Valhalla, New York
  • Chavakij Bhoomibunchoo
    The Einhorn Clinical Research Center and Bendheim Family Retina Center, Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • Nicole Scripsema
    The Einhorn Clinical Research Center and Bendheim Family Retina Center, Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • James Saunders
    The Einhorn Clinical Research Center and Bendheim Family Retina Center, Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York
    Rush Medical College, Chicago, Illinois
  • Richard B. Rosen
    The Einhorn Clinical Research Center and Bendheim Family Retina Center, Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, New York Medical College, Valhalla, New York
  • Footnotes
    Commercial Relationships  Apurva K. Patel, None; Gennady Landa, None; Chavakij Bhoomibunchoo, None; Nicole Scripsema, None; James Saunders, None; Richard B. Rosen, OD-OS Clarity (C), OPKO-OTI/Optos (C), Topcon Medical Systems, Inc (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 2156. doi:
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      Apurva K. Patel, Gennady Landa, Chavakij Bhoomibunchoo, Nicole Scripsema, James Saunders, Richard B. Rosen; Retinal Blood Flow in Patients with Sickle Cell Retinopathy assessed by Retinal Function Imager. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2156.

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Abstract

Purpose: : To evaluate retinal blood flow velocities in patients with sickle cell retinopathy(SCR) by using Retinal Function Imager (RFI).

Methods: : Fifteen patients with SCR underwent testing with the RFI. A comparison to the values of normal subjects was performed.

Results: : In the eyes of patients with sickle cell retinopathy, mean arterial and venous blood flow velocities were measured as 3.07+0.71 mm/sec and 2.12+0.54 mm/sec, respectively. While both arterial and venous velocities were found to be reduced in patients with SCR in comparison to normal subjects, only for retinal venous blood flow velocity there was a statistically significant difference (p=0.115 for arterial and p=0.003 for venous blood flow velocity).

Conclusions: : Reduced retinal blood flow may play an important role in the development of sickle cell retinopathy.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • vascular occlusion/vascular occlusive disease • blood supply 
© 2012, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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