March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Retinal Oxygen Saturation during Hyperoxia in Healthy Individuals
Author Affiliations & Notes
  • Olof B. Olafsdottir
    Ophthalmology, University of Iceland, Reykjavik, Iceland
  • Thorunn S. Eliasdottir
    Ophthalmology, University of Iceland, Reykjavik, Iceland
  • Jona V. Kristjansdottir
    Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
    Oxymap ehf., Reykjavik, Iceland
  • Sveinn H. Hardarson
    Ophthalmology, University of Iceland, Reykjavik, Iceland
    Oxymap ehf., Reykjavik, Iceland
  • Einar Stefánsson
    Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
    Oxymap ehf., Reykjavik, Iceland
  • Footnotes
    Commercial Relationships  Olof B. Olafsdottir, None; Thorunn S. Eliasdottir, None; Jona V. Kristjansdottir, Oxymap ehf. (E); Sveinn H. Hardarson, Oxymap ehf. (I, E, P); Einar Stefánsson, Oxymap ehf. (I, P, S)
  • Footnotes
    Support  Icelandic Research Council, Landspitali - University Hospital Research Fund
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 2166. doi:https://doi.org/
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    • Get Citation

      Olof B. Olafsdottir, Thorunn S. Eliasdottir, Jona V. Kristjansdottir, Sveinn H. Hardarson, Einar Stefánsson; Retinal Oxygen Saturation during Hyperoxia in Healthy Individuals. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2166. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To detect whether hyperoxia affects oxygen saturation in retinal arterioles and venules in healthy individuals. To test the sensitivity of a retinal oximeter.

Methods: : Retinal vessel oxygen saturation was measured in 31 healthy individuals with a spectrophotometric retinal oximeter (Oxymap ehf., Reykjavik, Iceland). Oximetry was performed during breathing of room air, during breathing of 100% O2 (10 minutes, 6L/min) and then again during breathing of room air (10 minutes recovery). Statistical analysis was performed with Student’s t-test for paired measurements.

Conclusions: : The retinal oximeter measures stable baselines and is sensitive to changes in O2 saturation and vessel diameter. Breathing 100% O2 increases oxygen saturation in retinal arterioles and venules and constricts them compared to normoxic levels.

Keywords: oxygen • retina • imaging/image analysis: clinical 
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