Purchase this article with an account.
Hong T. Liu, Millena Bittencourt G. Bittencourt, Mohanmed Ibrahim, Kristen Bowles, Yasir Sepah, Owhofasa Agbedia, Jithin Yohannan, Afsheen Khwaja, Diana V. Do, Quan D. Nguyen; Comparison Of Retinal Sensitivity In Normal Subjects Using Two Types Of Microperimetry Devices. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2204.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To evaluate the comparability and potential correlation of retinal light sensitivity obtained by Nidek MP-1™ (Nidek Technologies, Italy) and OPKO Spectral-OCT/SLO™ (OPKO Health Inc., USA).
Subjects with no known ocular diseases were enrolled in the study. The inclusion criteria were best-corrected visual acuity of 20/20 or better with a refractive error within ±6 diopters (D) and astigmatism within ±1.0 D. Both eyes of each subject were tested using MP-1 and the Spectral-OCT/SLO™. The test settings are summarized in Table 1.
14 normal subjects (25 eyes) with a mean age of 31 years (range: 20-45 years) were enrolled. 3 eyes were excluded due to poor foveal fixation or high refractive error. The mean spherical equivalent refractive error was -2.47DS (range +0.50 to -6.00 DS). The results of the retinal light sensitivity comparisons are summarized in Table 2. The sensitivity of the 4 central points in the pattern was also evaluated and the results are summarized in Table 3.
The lack of correlation between MP1 and SD OCT/SLO™ may be explained by the intrinsic difference in background luminance between devices and stimulus attenuation scale, creating different stimulus-contrast and retinal light adaption. Our pilot study has shown that it is unlikely for the MP1 and SD OCT/SLO to be used interchangeably. SD OCT/SLO™ offers a wider range of sensitivity detection, which may allow finer differentiation of retinal sensitivity. However, additional studies, with a greater number of subjects among other factors, are indicated to confirm our findings.
This PDF is available to Subscribers Only