Abstract
Purpose: :
To evaluate the efficacy of chronic treatment with autologous serum eyedrops in severe ocular surface disorders
Methods: :
Retrospective observational study. 203 patients (mean age: 51.4 years) unresponsive to conventional treatment were treated with 20% (n=56) or 50% autologous serum (n=207).Outcome measures included age, gender, ocular and medical history, initial symptoms, previous ocular surgery, concomitant systemic or topical treatment, visual acuity and conjuntival/corneal staining (Oxford scale). For statistical purposes, 7 groups were analized. 1. Dry eye, 2. Chronic or inflamatory LSCD, 3. non-inflamatory LSCD, 4. PED, 5. LASIK surgery; 6. Corneal surgery and 7. Others.
Results: :
Autologous serum were used for 95.3 (20%) and 88.2 (50%) weeks.
Conclusions: :
Autologous serum eyedrops is a safe and efficient treatment to provide essential components to the ocular surface
Keywords: clinical (human) or epidemiologic studies: outcomes/complications • cornea: tears/tear film/dry eye • cornea: epithelium