April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Optical Coherence Tomographic findings in Acute Exudative Polymorphous Vitelliform Maculopathy
Author Affiliations & Notes
  • Claudia Brue
    Clinica Oculistica, VRM, New York, New York
  • Footnotes
    Commercial Relationships  Claudia Brue, None
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Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2143. doi:
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      Claudia Brue; Optical Coherence Tomographic findings in Acute Exudative Polymorphous Vitelliform Maculopathy. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2143.

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      © ARVO (1962-2015); The Authors (2016-present)

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To report previously not appreciated findings in the early phase of acute exudative polymorphous vitelliform maculopathy (AEPVM).


Thirteen patients diagnosed with AEPVM were retrospectively analyzed, looking for the presence of inner and outer retinal cystic changes. Multi-modal imaging with color photography, fluorescein angiography (FA), fundus autofluorescence photography (FAF) and optical coherence tomography (OCT) obtained during the course of the disease was evaluated.


All patients presented with typical multiple, bilateral, symmetric sensory retinal detachments in the posterior pole. OCT imaging showed large, dome-shaped serous detachments in the central macula of 19 of 26 (73%) eyes, and multiple, smaller, bleb-like detachments in the macula of 23 of 26 (88%) eyes. Cystic spaces involving the inner and outer retina without leakage on FA, were observed in 15 of 26 (58%) patients during the initial phase of the disease.


Angiographically silent inner and outer retinal cystic cavities within the macular detachment are a common finding in the early phase of AEPVM. This finding may aid in gaining a better understanding of the pathologic mechanisms underlying this rare disease.

Keywords: retina • image processing • retinal degenerations: cell biology 

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