April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Optical Coherence Tomographic findings in Acute Exudative Polymorphous Vitelliform Maculopathy
Author Affiliations & Notes
  • Claudia Brue
    Clinica Oculistica, VRM, New York, New York
  • Footnotes
    Commercial Relationships  Claudia Brue, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2143. doi:
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      Claudia Brue; Optical Coherence Tomographic findings in Acute Exudative Polymorphous Vitelliform Maculopathy. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2143.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To report previously not appreciated findings in the early phase of acute exudative polymorphous vitelliform maculopathy (AEPVM).

 
Methods:
 

Thirteen patients diagnosed with AEPVM were retrospectively analyzed, looking for the presence of inner and outer retinal cystic changes. Multi-modal imaging with color photography, fluorescein angiography (FA), fundus autofluorescence photography (FAF) and optical coherence tomography (OCT) obtained during the course of the disease was evaluated.

 
Results:
 

All patients presented with typical multiple, bilateral, symmetric sensory retinal detachments in the posterior pole. OCT imaging showed large, dome-shaped serous detachments in the central macula of 19 of 26 (73%) eyes, and multiple, smaller, bleb-like detachments in the macula of 23 of 26 (88%) eyes. Cystic spaces involving the inner and outer retina without leakage on FA, were observed in 15 of 26 (58%) patients during the initial phase of the disease.

 
Conclusions:
 

Angiographically silent inner and outer retinal cystic cavities within the macular detachment are a common finding in the early phase of AEPVM. This finding may aid in gaining a better understanding of the pathologic mechanisms underlying this rare disease.

 
Keywords: retina • image processing • retinal degenerations: cell biology 
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