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Andre M. Gomes, Thais S. Mendes, Michele M. Freitag; Increased Foveal Area As A Risk Factor In The Idiopathic Macular Hole Development. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2159.
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to evaluate the foveal area of fellow eyes in patients with idiopathic macular hole as compared to a control group, using Spectral Domain optical coherence tomography (SD-OCT) image. The entire physiopathology process of idiopathic macular holes is yet to be determined.
fifty eyes of fifty patients were studied and divided in two groups. Group 1: 25 patients with macular hole in the fellow eye and group 2: 25 healthy individuals (control group). SD-OCT horizontal cross line images were obtained using a RT-vue 100 (Opto). The widest foveal picture was selected on each patient. Three different retina specialists measured total bidimensional foveal areas using the instrument caliper. A T-test was used to verify the difference between age and foveal area for both groups.
the mean foveal area in Group 1 was 0,159 (0,03) mm2 and in Group 2 was 0,079 (0,01) mm2. The difference between the two groups was statistically significantly (p<0,001), with Group 1 showing much larger measurements. There was no gender and age difference between groups.
foveal areas in fellow eyes of patients with idiopathic macular holes tend to be wider than in normal eyes as presented on SD-OCT. An increased foveal area in combination with other risk factors, like vitreous traction, may play a role in the pathophysiologic process of idiopathic macular hole formation. There have been few reports evaluating foveal morphology in recent years, but none have reported a correlation between an increased fovea and a higher risk for the development of macular holes. The SD-OCT is a helpful tool that allows a detailed analysis of the fovea.
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