April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Increased Foveal Area As A Risk Factor In The Idiopathic Macular Hole Development
Author Affiliations & Notes
  • Andre M. Gomes
    Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil
    Ophthalmology, Suel Abujamra Institute, Sao Paulo, Brazil
  • Thais S. Mendes
    Ophthalmology, Suel Abujamra Institute, Sao Paulo, Brazil
  • Michele M. Freitag
    Ophthalmology, Suel Abujamra Institute, Sao Paulo, Brazil
  • Footnotes
    Commercial Relationships  Andre M. Gomes, None; Thais S. Mendes, None; Michele M. Freitag, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2159. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Andre M. Gomes, Thais S. Mendes, Michele M. Freitag; Increased Foveal Area As A Risk Factor In The Idiopathic Macular Hole Development. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2159.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose: : to evaluate the foveal area of fellow eyes in patients with idiopathic macular hole as compared to a control group, using Spectral Domain optical coherence tomography (SD-OCT) image. The entire physiopathology process of idiopathic macular holes is yet to be determined.

Methods: : fifty eyes of fifty patients were studied and divided in two groups. Group 1: 25 patients with macular hole in the fellow eye and group 2: 25 healthy individuals (control group). SD-OCT horizontal cross line images were obtained using a RT-vue 100 (Opto). The widest foveal picture was selected on each patient. Three different retina specialists measured total bidimensional foveal areas using the instrument caliper. A T-test was used to verify the difference between age and foveal area for both groups.

Results: : the mean foveal area in Group 1 was 0,159 (0,03) mm2 and in Group 2 was 0,079 (0,01) mm2. The difference between the two groups was statistically significantly (p<0,001), with Group 1 showing much larger measurements. There was no gender and age difference between groups.

Conclusions: : foveal areas in fellow eyes of patients with idiopathic macular holes tend to be wider than in normal eyes as presented on SD-OCT. An increased foveal area in combination with other risk factors, like vitreous traction, may play a role in the pathophysiologic process of idiopathic macular hole formation. There have been few reports evaluating foveal morphology in recent years, but none have reported a correlation between an increased fovea and a higher risk for the development of macular holes. The SD-OCT is a helpful tool that allows a detailed analysis of the fovea.

Keywords: macular holes • retina • macula/fovea 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.