April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Fourier-domain Optical Coherence Tomography (OCT) Imaging In Patients With History of Retinopathy Of Prematurity (ROP)
Author Affiliations & Notes
  • Wei-Chi Wu, II
    Ophthalmology, Chang Gung Memorial Hosp, Taoyuan, Taiwan
  • Chi-Chun Lai
    Ophthalmology, Chang Gung Memorial Hosp, Taoyuan, Taiwan
  • Footnotes
    Commercial Relationships  Wei-Chi Wu, II, None; Chi-Chun Lai, None
  • Footnotes
    Support  Partly supported by National Science Council, Taipei, Taiwan, NSC98-2311-B-182A-001-MY2 and Chang Gung Memorial Hospital Research Grant, Taoyuan, Taiwan, CMRPG 370751
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2177. doi:
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      Wei-Chi Wu, II, Chi-Chun Lai; Fourier-domain Optical Coherence Tomography (OCT) Imaging In Patients With History of Retinopathy Of Prematurity (ROP). Invest. Ophthalmol. Vis. Sci. 2011;52(14):2177.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : The purpose of this study is to determine the Fourier-domain optical coherence tomography (OCT) findings for children with a history of retinopathy of prematurity (ROP) and to identify any association between OCT findings and patients’ visual acuity.

Methods: : Children 6 to 14 years of age with history of prematury (group 1, 2, 3) and age-matched normal children (group 4) were included prospectively. Fourier-domain OCT was used to document the status of macula and the results were compared. Patients were classified into the following 4 groups: patients with history of ROP and laser or cryo-therapy (group 1); with regressed ROP without any treatment (group 2); with prematurity history without ROP (group 3); and normal full term children (group 4). Patients’ visual acuity, refractive status, axial length, and corneal keratometry were also measured and compared among different groups of patients.

Results: : Sixty-nine patients were enrolled in the study. Patients in group 1 had significantly thicker macula as demonstrated by OCT than the rest of patients. The incidence of abnormal foveal contour in group 1 was also significantly higher than the rest of patients. These findings correlated with poorer visual acuity and higher refractive error identified in group 1 patients.

Conclusions: : Patients with treatment-requiring ROP is more likely to have abnormal foveal development and worse visual prognosis than the other groups of patients. Fourier-domain OCT is an useful tool for detecting subtle changes in the macular region in the patients with history of ROP.

Keywords: retinopathy of prematurity • retinal development • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 

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