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Rajeev K. Pappuru, Uday Kumar Addepalli, Lalitha Y, Harsha Rao, Eric B. Papas, Rohit C. Khanna, Ganesh babu Jonnadula, Chandra Sekhar Garudadri; Effect Of Age On Normal Choroidal Thickness Measurement By Cirrus High Definition Optical Coherence Tomography (hd-oct). Invest. Ophthalmol. Vis. Sci. 2011;52(14):2184.
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To evaluate the effect of age on choroidal thickness measured by Cirrus HD-OCT in normal Indian eyes
A prospective observational study with 87 eyes of 55 subjects (17 male: 38 female) underwent macular imaging with Cirrus HD 5 line raster scan mode. Choroidal thickness was measured by a single technician from the lower border of the retinal pigment epithelium to the lower border of choroid. The measurements were made at the fovea and at 5 points nasal and 5 points temporal to the fovea each separated by a distance of 500 microns. Effect of age on the choroidal thickness was assessed using linear mixed modelling approach.
The mean (± standard deviation) age of the subjects was being 48.6 ± 12.3 years (range 11 to 75 years).Choroidal thickness at the fovea was 255 ± 66 microns. Choroidal thickness 500, 1000, 1500, 2000 and 2500 microns from the fovea nasally were 239 ± 57, 230 ± 54, 237 ± 57, 232 ± 47 and 232 ± 44 respectively. Similar measurements temporal to the fovea were 238 ± 64, 230 ± 58, 233 ± 50, 239 ± 56 and 233 ± 53 respectively. Choroidal thickness at the fovea was significantly greater than that at all points temporal and nasal to fovea. Age did not have an effect on the thickness measurements at any of these points (p>0.2 for all analyses).
Choroidal thickness at the fovea was significantly greater than the thickness at points upto 2500 microns in the perifoveal region. Choroidal thickness of normal subjects did not vary with age.
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