April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Spectral Domain OCT Findings in Patients with Polypidal Choroidal Vasculopathy
Author Affiliations & Notes
  • Takeya Kohno
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
  • Manabu Yamamoto
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
  • Hisashi Iwami
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
  • Shinsuke Ataka
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
  • Mayumi Kaida
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
  • Michiko Hirabayashi
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
    Ophthalmology, Shiraniwa Hospital, Ikoma, Japan
  • Kunihiko Shiraki
    Ophthalmology & Visual Science, Osaka City Univ Grad Sch of Med, Osaka, Japan
  • Footnotes
    Commercial Relationships  Takeya Kohno, None; Manabu Yamamoto, None; Hisashi Iwami, None; Shinsuke Ataka, None; Mayumi Kaida, None; Michiko Hirabayashi, None; Kunihiko Shiraki, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2200. doi:
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      Takeya Kohno, Manabu Yamamoto, Hisashi Iwami, Shinsuke Ataka, Mayumi Kaida, Michiko Hirabayashi, Kunihiko Shiraki; Spectral Domain OCT Findings in Patients with Polypidal Choroidal Vasculopathy. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2200.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To elucidate the spectral domain optical coherence tomography (SD-OCT) findings in patients with polypoidal choroidal vasculopathy (PCV).

Methods: : 73 eyes of 73 Japanese patients having PCV were examined by indocyanine green angiography (IA) and SD-OCT (HRA-OCT Spectralis, Heiderberg Engineering). The near-infrared image or IA image and the SD-OCT image were compared using the point-to point correlation feature of HRA-OCT Spectralis. Each section was comprised of more than 20 averaged scans.

Results: : Polypoidal dilations of the terminal of the branch vessels were seen on IA in all eyes. On SD-OCT, detached retinal pigment epithelium (RPE) from Bruch’s membrane (BM) was observed in accordance with the range of the branch vessels and polypoidal dilations on IA. The part of polypoidal dilations upheaved steeply and the part of the branch vessels upheaved gently. Their internal reflection was not uniform and the findings which look like hemal cavity were observed. BM was visualized as distinct high reflective line in the whole PCV lesions except the areas of large polypoidal dilations and marked serous RPE detachment. In 30 eyes, the dip and/or breaks of the BM were observed around the bifurcation of the branch vessels on IA. The superficial choroid and the sub-RPE space were connected through the dip and/or breaks of the BM.

Conclusions: : SD-OCT demonstrated that the branch vessels and the polypoidal dilations of the PCV exist between the detached RPE and BM. In addition, abnormal vasculature beneath the RPE and the changes of BM associated with the branch vessels may be detectable with some cases.

Keywords: age-related macular degeneration • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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