Purchase this article with an account.
Seung-Young Yu, Eung-Suk Kim, Young-Seob Lee, Hyung-Woo kwak; Correlation Between Foveal Microstructure and Visual Outcome in Surgically Closed Macular Holes: SD-OCT Analysis and FAF Findings. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2210.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To investigate the change of foveal microstructure and identify correlation with visual acuity, and fundus autofluorescence (FAF) findings in eyes with surgically closed macular hole.
Twenty eyes in 20 patients with successful closure of macular hole were studied. The eyes were categorized into 3 groups according to restoration of the IS/OS junction and ELM signal in the SD-OCT finding 6 months after the operation: Group A with complete restoration of the IS/OS junction and the ELM; Group B with a restoration of ELM, but not of IS/OS junction; and Group C with restoration of neither ELM nor IS/OS junction. The FAF findings of fovea at postoperative 6 month were classified as normal autofluorescence, mild increase of autofluorescence, and marked increase of autofluorescence.The correlation between postoperative best-corrected visual acuity (BCVA), FAF findings and restoration of photoreceptor inner and outer segment (IS/OS) junction and external liming membrane (ELM) were investigated.
The baseline BCVA did not differ significantly (P=0.089) among groups, but 6 months after the operation, BCVA (logMAR) of group A (9 eyes, 0.33±0.46) and B (6 eyes, 0.42±0.37) were significantly better than group C (5 eyes, 1.17±0.43) (P=0.03, P=0.046).The BCVA of group with marked increase of autofluorescence was significantly low than other groups (P=0.013, P=0.049). In group A, 9 eyes showed normal autofluorescence, in group B, 8 eyes showed normal or mild increase of autofluorescence, and in group C, 3 eyes showed marked increase of autofluorescence.
The postoperative reconstruction of ELM as well as IS/OS junction may play an important role in visual recovery after macular hole surgery. In addition, postoperative FAF findings can be used for assess of recovery of outer retinal structure.
This PDF is available to Subscribers Only