March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Davinci’s Green: A New Vital Dye to Stain Internal limiting Membrane and Tissues in Intraocular Surgery
Author Affiliations & Notes
  • Juan D. Arias, Sr.
    oncology, Wills Eye Institute, Philadelphia, Pennsylvania
    the Retina and Vitreous Service, Clinica Oftalmológica Centro Caracas, Caracas, Venezuela
  • Martin Serrano
    the Retina and Vitreous Service, Clinica Oftalmológica Centro Caracas, Caracas, Venezuela
  • J. Fernando Arevalo
    Vitreoretinal, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
    Retina Division, Wilmer Eye Institute, Baltimore, Maryland
  • Footnotes
    Commercial Relationships  Juan D. Arias, Sr., None; Martin Serrano, None; J. Fernando Arevalo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 2637. doi:
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    • Get Citation

      Juan D. Arias, Sr., Martin Serrano, J. Fernando Arevalo; Davinci’s Green: A New Vital Dye to Stain Internal limiting Membrane and Tissues in Intraocular Surgery. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2637.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To evaluate the ability of Davinci’s Green (DG), a new vital dye to stain lens capsule (LC), internal limiting membrane (ILM), and vitreous in porcine eyes.

 
Methods:
 

Experimental study in animal eyes. A new vital dye called Davinci's Green produced by mixing two known vital dyes (brilliant blue and sodium fluorescein) was injected on the LC and ILM of enucleated porcine eyes. The vitreous was stained with 2 mL of the dye mixture for 1 minute.

 
Results:
 

In porcine eyes, ILM staining with DG resulted in strong green staining. Vitreous examination revealed strong green staining. LC evaluation showed moderate staining with DG.

 
Conclusions:
 

Davinci’s Green seems to be a potential good option as vital dye with strong affinity for the ILM and the vitreous, and moderate affinity for the lens capsule in porcine eyes. Additional studies are needed to analyze the biocompatibility of DG with the human eye.  

 
Keywords: macular holes • vitreoretinal surgery • retina 
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