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Ricardo Cuina, Jose M. Vazquez-Molini, Silvia Perez-Trigo, David Diaz-Valle, Pedro Arriola-Villalobos, Jose M. Benitez-del-Castillo; Visual Function and Keratometric Study in Patients with Keratoconus Treated with Cross-linking. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2545.
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© ARVO (1962-2015); The Authors (2016-present)
To study uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), contrast sensitivity (CS), aberration coefficient (ABR), and maximun keratometry (Kmax) and medium keratometry (Km) in patients with keratoconus treated with cross-linking.
A longitudinal study performed in 17 eyes (17 patients) with keratoconus type 2-3 (Amsler classification) treated with cross-linking. The UCVA and BCVA were assessed by ETDRS test. CS with and without correction was studied with the Pelli-Robson test. ABR, Kmax and Km were evaluated with Pentacam Scheimpflug corneal topographer. Data were obtained before treatment, and 1, 3, 6, and 12 months pos-treatment. The statistical study was performed with Statgraphics 5.1 by comparing paired groups and using the Wilcoxon's signed range test.
A statistically significant difference (p<0.05) was observed in ABR before and 12 months after treatment with a mean reduction of 0.4. UCVA improved 0.14 logMar units with a statistical significant difference (p<0.05) before and 12 months after treatment. The other studied data did not show statistically significant differences.
Cross-linking seems to improve UCVA and ABR in keratoconus patients (type 2-3) but not difference was evidenced in BCVA, Kmax, Km and CS.
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