April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Visual Function and Keratometric Study in Patients with Keratoconus Treated with Cross-linking
Author Affiliations & Notes
  • Ricardo Cuina
    Hospital Clinico San Carlos Madrid, Madrid, Spain
  • Jose M. Vazquez-Molini
    Hospital Clinico San Carlos Madrid, Madrid, Spain
  • Silvia Perez-Trigo
    Hospital Clinico San Carlos Madrid, Madrid, Spain
  • David Diaz-Valle
    Hospital Clinico San Carlos Madrid, Madrid, Spain
  • Pedro Arriola-Villalobos
    Hospital Clinico San Carlos Madrid, Madrid, Spain
  • Jose M. Benitez-del-Castillo
    Hospital Clinico San Carlos Madrid, Madrid, Spain
  • Footnotes
    Commercial Relationships  Ricardo Cuina, None; Jose M. Vazquez-Molini, None; Silvia Perez-Trigo, None; David Diaz-Valle, None; Pedro Arriola-Villalobos, None; Jose M. Benitez-del-Castillo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2545. doi:https://doi.org/
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      Ricardo Cuina, Jose M. Vazquez-Molini, Silvia Perez-Trigo, David Diaz-Valle, Pedro Arriola-Villalobos, Jose M. Benitez-del-Castillo; Visual Function and Keratometric Study in Patients with Keratoconus Treated with Cross-linking. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2545. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To study uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), contrast sensitivity (CS), aberration coefficient (ABR), and maximun keratometry (Kmax) and medium keratometry (Km) in patients with keratoconus treated with cross-linking.

 
Methods:
 

A longitudinal study performed in 17 eyes (17 patients) with keratoconus type 2-3 (Amsler classification) treated with cross-linking. The UCVA and BCVA were assessed by ETDRS test. CS with and without correction was studied with the Pelli-Robson test. ABR, Kmax and Km were evaluated with Pentacam Scheimpflug corneal topographer. Data were obtained before treatment, and 1, 3, 6, and 12 months pos-treatment. The statistical study was performed with Statgraphics 5.1 by comparing paired groups and using the Wilcoxon's signed range test.

 
Results:
 

A statistically significant difference (p<0.05) was observed in ABR before and 12 months after treatment with a mean reduction of 0.4. UCVA improved 0.14 logMar units with a statistical significant difference (p<0.05) before and 12 months after treatment. The other studied data did not show statistically significant differences.

 
Conclusions:
 

Cross-linking seems to improve UCVA and ABR in keratoconus patients (type 2-3) but not difference was evidenced in BCVA, Kmax, Km and CS.

 
Keywords: keratoconus • topography • contrast sensitivity 
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