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Wasfeh Musheinesh, Bret Hughes, Mark Juzych, Anju Goyal, Aman Shukairy, Monica Alexander, Chaesik Kim; Effectiveness of 360 Degree Selective Laser Trabeculoplasty at 24 Months: A Retrospective Analysis. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2623.
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To analyze the effectiveness of 360 degree Selective Laser Trabeculoplasty (SLT) in lowering intraocular pressure (IOP) in patients with open angle glaucoma using topical medication.
This is a retrospective chart review of patients with open angle glaucoma and uncontrolled IOP who underwent 360 degree SLT. Demographic information was cataloged preoperatively; IOP and medications were recorded pre and postoperatively, and followed for 24 months. Patients were divided into two groups: patients on 2 or more topical medications versus patients on 1 or less. Paired and unpaired t-tests and Kaplan-Meier survival were used to compare the two groups. A 20% IOP reduction with equivalent or reduced amount of glaucoma medication during follow-up and without surgery was considered a success for criteria 1. A reduction in IOP by 20% and without surgery during follow-up was considered success for criteria 2.
A total of 160 eyes of 160 patients were analyzed. Sixty-two patients had ≤1 pre-SLT medication (group A); 98 had >1 pre-SLT medication (group B). Demographics including age, race, sex, diabetes mellitus (DM), and hypertension (HTN) did not differ statistically between groups (p > 0.15). Patient demographics include Group A (85% African Americans, 15% Caucasians, 42 females, 20 males, mean age 71 years, 31% with DM, 74% with HTN) and Group B (72% African American, 28% Caucasian, 62 females, 37 males, mean age 69 years, 29% with DM, 67% with HTN). There was a statistically higher survival rate in group A than group B post-SLT for both criteria 1 and criteria 2 (p = 0.008, p = 0.002 respectively, log rank test).
There is greater IOP reduction with 360 degree SLT among patients using 1 glaucoma medication compared to patients using 2 or more glaucoma medications.
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