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Megumi Yatera, Takeya Kohno, Manabu Yamamoto, Yusaku Yoshida, Tasuku Yoneda, Hisashi Iwami, Mayumi Kaida, Yoshio Okazaki, Kunihiko Shiraki; Fundus Autoflurescence Of Choroidal Neovascular Lesions In High Myopic Eyes Studied With Different Wavelengths Of Excitation Light Using Heidelberg Retina Angiogram And A Fundus Camera System. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2718.
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© ARVO (1962-2015); The Authors (2016-present)
To examined fundus autofluorescence (FAF) of choroidal neovascular (CNV) lesions in high myopic eyes when Heidelberg retina angiogram (HRA) and a fundus camera system with different wavelengths of excitation light were used.
Fundus angiographic files taken between January 2009 and November 2010 were reviewed. Eyes, of which FAF had been taken using HRA with a 488nm laser and a Topcon fundus camera system with three sets of different excitation bandpass filters: central wavelengths of 520nm, 580nm, and either of 620nm or 720nm, were included in the study. High myopic eyes were identified according to HRA infrared images, color fundus pictures, and fluorescein angiograms (FAG). CNV lesions were localized in FAGs and confirmed in optical coherence tomography images.
Thirty two eyes of 32 patients (10 males and 22 females, 36 to 85 years old) were identified to have CNV in addition to high myopic fundus changes. 19 eyes were phakic with a range of -6.375 to -20.38 diopters of myopia, and the rest of 13 eyes were pseudophakic. Round or ring-shaped increased FAF corresponding to the CNV lesions was seen in 4 eyes (12.5%) with 488nm using HRA, 5 eyes (15.7%) with 520nm, 9 eyes (28%) with 580nm and 23 eyes (72%) with 660nm or 720nm using the fundus camera out of the 32 eyes. A part of the CNV lesion showed increased FAF in 15 eyes with HRA, 12 eyes with 520nm, 18 eyes with 580nm, 8 eyes with 660nm or 720nm. The graded scale analysis of FAF at the CNV lesions showed a significant difference in its FAF appearance when the different apparatus and excitation light of different wavelengths were used.(p<0.01).
FAF of the CNV lesions in high myopic eyes was seen well with the excitation light centering at 660nm or 720nm.
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