April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Evaluation of Crystalline Lens Waterclefts by Image Analysis. Reykjavik Eye Study
Author Affiliations & Notes
  • Kota Nagai
    Ophthalmology, Nagai eye clinic, Ibaraki, Japan
    Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • Yasuo Sakamoto
    Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • Natsuko Hatsusaka
    Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • Tetudai Mita
    Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • Masami Kojima
    Div of Vis Rsrch for Environ Hlth,
    Kanazawa Medical University, Uchinada, Japan
  • Yutaka Kawakami
    Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • Kazuyuki Sasaki
    Div of Vis Rsrch for Environ Hlth,
    Kanazawa Medical University, Uchinada, Japan
    Rehabilitation Faculty of Medical Science and Welfare, Tohoku Bunka Gakuen University, Sendai, Japan
  • Hiroshi Sasaki
    Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • Fridbert Jonasson
    Ophthalmology, University of Iceland, Reykjavik, Iceland
  • Footnotes
    Commercial Relationships  Kota Nagai, None; Yasuo Sakamoto, None; Natsuko Hatsusaka, None; Tetudai Mita, None; Masami Kojima, None; Yutaka Kawakami, None; Kazuyuki Sasaki, None; Hiroshi Sasaki, None; Fridbert Jonasson, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2796. doi:
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      Kota Nagai, Yasuo Sakamoto, Natsuko Hatsusaka, Tetudai Mita, Masami Kojima, Yutaka Kawakami, Kazuyuki Sasaki, Hiroshi Sasaki, Fridbert Jonasson; Evaluation of Crystalline Lens Waterclefts by Image Analysis. Reykjavik Eye Study. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2796.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Waterclefts (WC) are fiber-based opacities usually located at the y-sutures in the superficial cortical zone. Eyes with WC show higher coma and trefoil aberrations causing reduced visual function, but the effect is difficult to evaluate precisely. We investigated use of image processing in evaluation of WC.

Methods: : Among the 573 participants aged 50 years or older of the Reykjavik Eye Study (RES) in 2008, 29 right eyes (13 male; 16 female; mean±SD age 71.8±4.3 years) with WC were compared with 194 transparent right eyes (97 male; 97 female; mean±SD age 66.8±4.5 years) from retroillumination images by anterior eye segment analysis system (EAS-1000, NIDEK). Optical function was evaluated by wavefront analyzer (KR9000PW, Topcon) for higher order aberrations (HOA) and point spread function analyzer (PSF-1000, Topcon) for retinal image contrast. Retroillumination images were analyzed by Fast Fourier Transform and standardization of level. WC was quantified by optical irregularity in the 4 mm diameter pupillary area. Correlations between optical irregularity and HOA, and retinal image contrast were investigated.

Results: : WC as optical irregularity within the optical zone of 4.0mm ranged through 1.65~4.19. There was no significant correlation between optical irregularity and three types of internal ocular total HOA (coma, trefoil, spherical) for optical zones of 4.0mm and 6.0mm. There was a significant correlation between optical irregularity and retinal image contrast of 0.7,0.8logMAR index with optical zones of 3.0mm

Conclusions: : There was significant correlation between WC as an optical irregularity and retinal image contrast, and, so this image analyses method could be useful to evaluate WC.

Keywords: cataract • imaging/image analysis: clinical • crystallins 
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