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Yan Wang, Lin Zhang, Lu Wang, Xiaoyan Yang, Weili Geng, Ying Jin, Tong Zuo, Refractive Surgery & Vision Correction Institute; Optical Quality of Ten Years following Photorefractive Keratectomy for Myopic Eyes. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2848.
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To investigate the optical quality with a ten years follow-up after photorefractive keratectomy (PRK) for low to moderate myopia.
24 patients (45 eyes) underwent PRK using the NIDK EC-5000 excimer laser platform with low to moderate refractive powers(mean, -4.92±1.18D). Three control-matched groups were set: 36 eyes with Epi-LASIK surgery, which represents the surface ablation, and 30 eyes in LASIK group which represents lamella ablation, and those preoperative data. Wavefront aberrations were measured and calculated for a 6-mm pupil using a Hartmann-Shack sensor for the group10 years with PRK and preoperatively and 4 to 6 months after Epi-LASIK and LASIK procedures.
On average, PRK induced a significant (P=0.00) 2.3 -fold increase in the HOA RMS at 10 years after surgery compared to matched preoperative level. The main contribution was the increasing (3.5-fold) of spherical aberration and (3.1-fold) spherical-like aberrations (S4). Moreover, spherical aberration (Z12) showed a statistically higher increase (P=0.02) in 10 years group, and followed by post-LASIK and post-Epi-LASIK groups, which displayed the similar characters as those of the spherical-like aberrations. However, there was no significant difference of the postoperative coma-like aberrations (S3) between the 3 types of surgery, or between long and short time postoperatively. In addition, from HOA, it showed no difference between different types of surface ablation (PRK and Epi-LASIK), no matter their follow-up periods were different, and the significant difference focused on different types of ablation (lamella and surface ablation).
(1) Refractive surgery induces important amounts of the HOAs, even for long term. (2) The largest increase occurs for spherical and spherical-like aberrations in eyes at 10 years post-PRK, both rising by more than 3 times. (3) The 3rd order aberrations showed no significant difference in any postoperative state or any ablation types.
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