April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Age and Axial Length Correlation with Macular Retinal Thickness
Author Affiliations & Notes
  • John Frisbee
    Ophthalmology, State University of New York, Downstate Medical Center, Brooklyn, New York
  • Ramanath Bhandari
    Ophthalmology, State University of New York, Downstate Medical Center, Brooklyn, New York
  • Alex Kartvelishvili
    Ophthalmology, State University of New York, Downstate Medical Center, Brooklyn, New York
  • Douglas Lazzaro
    Ophthalmology, State University of New York, Downstate Medical Center, Brooklyn, New York
  • Eric Shrier
    Ophthalmology, State University of New York, Downstate Medical Center, Brooklyn, New York
  • Footnotes
    Commercial Relationships  John Frisbee, None; Ramanath Bhandari, None; Alex Kartvelishvili, None; Douglas Lazzaro, None; Eric Shrier, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 3210. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      John Frisbee, Ramanath Bhandari, Alex Kartvelishvili, Douglas Lazzaro, Eric Shrier; Age and Axial Length Correlation with Macular Retinal Thickness. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3210.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : Few studies have been published comparing patient age, ocular axial length, and retinal thickness. These variables have been known for some time to correspond to a variety of retinal pathologies. Previously published papers have shown differences in opinion with regard to a correlation between these variables. The present study was performed to compare patient age, ocular axial length, and retinal thickness to correlate our findings both with previously published works and with pathology models.

Methods: : Our observational study compared 35 eyes of 22 volunteers, 13 female, 9 male, between the ages of 18 and 73. Volunteers were recruited between January 2010 and May 2010. Ocular axial length was measured using IOL Master (Carl Zeiss Meditech AG, IOLMaster with Advanced Technology, software v. 5.2.1, Jena, Germany), and retinal thickness was measured using an Optivue RTVue ft-OCT (Optovue Inc., RTVue ft-OCT, software v. 4.0.5.39, Fremont, CA) by MM5 section method analysis, evaluating inner, outer and full retinal thickness.

Results: : Ocular axial lengths were found to range between 21.5 mm and 31.3 mm (mean: 24.2 mm; median 23.8 mm). Foveal retinal thickness ranged between 193 µm and 282 µm with average retinal thickness ranging between 269 µm and 312 µm (mean 243.6 µm; median 245 µm). Using the Mann-Whitney-U test, there was no statistically significant difference in average macular thickness when compared to age, gender, or axial length.However, when comparing eyes with Axial lengths less than 23.8 mm as compared to those greater than 23.8 there was a statistically significant increase in the foveal thickness as axial length increased (p=0.017 by the Mann-Whitney U Test). Additionally, average outer macular thickness showed a corresponding decrease, but this trend did not reach statistical significance (p=0.09).

Conclusions: : Our findings showed no statistical difference in average retinal thickness with regard to ocular axial length, but did show a statistically significant increase in foveal thickness with increasing axial length, and a decreasing trend in peripheral macular thickness. We believe these findings may correspond to the increased clinical incidence of retinal pathology, like rhegmatogenous retinal detachment frequently found in patients with increased ocular axial length.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×