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Hernan Martinez-Osorio, Laia Rafat, Maria De la Paz, Jose Temprano, Gustavo A. Montenegro, Ralph Michael, Victor Charoenrook, Rafael I. Barraquer; Comparison Of Fibrin Glue And Sutures For Conjunctival Autograft In primary Pterygium Surgery. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3364.
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To compare pterygium excision conjunctival autograft surgery using Tissucol fibrin glue versus Nylon sutures.
Retrospective comparative case study. Forty one patients (mean age: 42.15 years) with primary pterygium were operated with sutured graft (n=19) or glued graft (n=21). Patients were operated by two surgeons. Standard conjunctival autograft was sutured with nylon (JT) or the autograft was placed with Tissucol fibrin glue (MP). Outcome measures included visual acuity, refraction, pterigyum area, complications and recurrence rates. Patients were followed up to at least 12 months.
There were no differences in skin's colour, iris's colour or pterygium's area among the groups. In both groups, darkest iris were more common (grade 3: n=19 or grade 4: n=14). More females were operated by fibrin glued conjunctival autografting (n=16) than sutured surgery (n=5) (p 0.001). There were no changes in visual acuity or refraction. At week 1, conjunctival hemorrhage was more frequent in the glue's group (n=10) than suture's group (n=0) (p 0.0002), as well as, conjunctival edema in glue's group (n=14) vs suture's group (n=7) (p 0.06). At 12 months, there were no recurrences in the glue's group and one recurrence in the suture's group (not significantly different).
Fibrin glued and sutured conjunctival autografting procedures are safe and effective methods for pterygium surgery. Conjunctival autograft with fibrin glue showed more complications than sutured surgery, however autograft recurrence rate at 12 months was not statistically significant between groups.
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