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Jin-Hyoung Kim, Eun Jung Jun, Nikki Camara, Tracy L. Purcell, David J. Schanzlin; The Change Of Bursting Strength In Sclera Tunnel Incision After Application Of An Adherent Ocular Bandage In Human Globes. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3377.
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To evaluate the effect of adherent ocular bandage for sclera tunnel incision in human eye globes.
Five research-grade whole globes from the San Diego Eye Bank were used to evaluate bursting strength for 2 groups. After making a 4mm scleral tunnel incision, leakage from the wound was examined using fluorescent strip and sponge. The busting strength was determined according to the bottle height of balanced salt solution which was irrigated into the anterior chamber of globe at a specified minimal height which wound leakage occurred. Bursting strengths were checked twice in same globe tissue prior to bandage application and 30seconds after application of adherent ocular bandage (ResureTM, Ocular Therapeuticx, Inc., MA, USA). The former data were classified as Group I and the latter as Group II. These bursting strengths, which were converted to mmHg, were compared between the two groups.
The mean bursting strength was 41.45±4.64 mm Hg (Mean±SD) in Group I and 72.18+1.06mmHg in Group II. Group II showed statistically significant higher bursting strength (p<0.001).
The adherent ocular bandage protected the incision effectively in ex vivo human globes immediately after surgery. The increased bursting strength after application of adherent bandage suggests the bandage might be helpful to enhance wound sealing effect before natural wound healing may occur.
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