April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Real-Time Imaging of Accommodation using Extended Depth Spectral Domain OCT
Author Affiliations & Notes
  • Marco Ruggeri
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Univ of Miami Miller School of Medicine, Miami, Florida
    Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, Univ of Miami, College of Engineering, Coral Gables, Florida
  • Stephen Uhlhorn
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Univ of Miami Miller School of Medicine, Miami, Florida
  • Carolina De Freitas
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Univ of Miami Miller School of Medicine, Miami, Florida
  • Fabrice Manns
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Univ of Miami Miller School of Medicine, Miami, Florida
    Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, Univ of Miami, College of Engineering, Coral Gables, Florida
  • Jean-Marie A. Parel
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Univ of Miami Miller School of Medicine, Miami, Florida
    Vision Cooperative Research Centre, Sydney, Australia
  • Footnotes
    Commercial Relationships  Marco Ruggeri, None; Stephen Uhlhorn, None; Carolina De Freitas, None; Fabrice Manns, None; Jean-Marie A. Parel, None
  • Footnotes
    Support  NEI Grant 2R01EY14225, P30EY14801 (Center Grant); Australian Government CRC Scheme (Vision CRC); Henri and Flore Lesieur Foundation (JMP); Florida Lions Eye Bank; Research to Prevent Blindness
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 3402. doi:
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    • Get Citation

      Marco Ruggeri, Stephen Uhlhorn, Carolina De Freitas, Fabrice Manns, Jean-Marie A. Parel; Real-Time Imaging of Accommodation using Extended Depth Spectral Domain OCT. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3402.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To image dynamics of the human crystalline lens in real-timeduring accommodation using spectral domain OCT with extendeddepth range.

 
Methods:
 

An SD-OCT system was developed to obtain images of the anteriorsegment of human eye with an imaging depth of 10.4 mm in airat an imaging rate of 40 frames/sec. The OCT system was usedto image the real-time dynamic response of the lens to a 10Daccommodative stimulus. Experiments were conducted on threesubjects aged 23, 34 and 42.

 
Results:
 

Images acquired on the 23 year old subject are shown below.The images show the movement of the iris, the steepening ofthe anterior lens surface and the thickening of the lens. Changeson the internal structure of the lens can also be observed.

 
Conclusions:
 

The study demonstrates the feasibility of imaging dynamics ofthe in vivo human lens during accommodation in real-time withextended axial range SD-OCT.Support: NEI Grant 2R01EY14225,P30EY14801 (Center Grant); Australian Government CRC Scheme(Vision CRC); Research to Prevent Blindness; Henri and FloreLesieur Foundation (JMP); Florida Lions Eye Bank.  

 

 
Keywords: accommodation • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment 
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