Real-Time Imaging of Accommodation using Extended Depth Spectral Domain OCT

Abstract

 

Purpose:

 

To image dynamics of the human crystalline lens in real-timeduring accommodation using spectral domain OCT with extendeddepth range.

 

Methods:

 

An SD-OCT system was developed to obtain images of the anteriorsegment of human eye with an imaging depth of 10.4 mm in airat an imaging rate of 40 frames/sec. The OCT system was usedto image the real-time dynamic response of the lens to a 10Daccommodative stimulus. Experiments were conducted on threesubjects aged 23, 34 and 42.

 

Results:

 

Images acquired on the 23 year old subject are shown below.The images show the movement of the iris, the steepening ofthe anterior lens surface and the thickening of the lens. Changeson the internal structure of the lens can also be observed.

 

Conclusions:

 

The study demonstrates the feasibility of imaging dynamics ofthe in vivo human lens during accommodation in real-time withextended axial range SD-OCT.Support: NEI Grant 2R01EY14225,P30EY14801 (Center Grant); Australian Government CRC Scheme(Vision CRC); Research to Prevent Blindness; Henri and FloreLesieur Foundation (JMP); Florida Lions Eye Bank.  

 

 

Keywords: accommodation • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment