April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Repeatability Of Diurnal Intraocular Pressure Measurements In Glaucoma Patients
Author Affiliations & Notes
  • Tarun Arora
    Ophthalmology, Glaucoma facility, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • Amit Sobti
    Ophthalmology, Glaucoma facility, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • Anita Panda
    Ophthalmology, Glaucoma facility, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • Sumeet Khanduja
    Ophthalmology, Glaucoma facility, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • Vishal Arora
    Ophthalmology, Glaucoma facility, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • Tanuj Dada
    Ophthalmology, Glaucoma facility, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • Footnotes
    Commercial Relationships  Tarun Arora, None; Amit Sobti, None; Anita Panda, None; Sumeet Khanduja, None; Vishal Arora, None; Tanuj Dada, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 3446. doi:
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    • Get Citation

      Tarun Arora, Amit Sobti, Anita Panda, Sumeet Khanduja, Vishal Arora, Tanuj Dada; Repeatability Of Diurnal Intraocular Pressure Measurements In Glaucoma Patients. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3446.

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Abstract
 
Purpose:
 

To evaluate the short-term repeatability of diurnal intraocularpressure (IOP) pattern in subjects with primary open glaucomaon chronic ocular hypotensive therapy.

 
Methods:
 

Thirty cases of primary open angle glaucoma (POAG) underwentdiurnal IOP estimation (7am to 10 pm; every 3 hrs) using Goldmanapplanation tonometer on 2 visits, 1 week apart. Intraclasscorrelation coefficient (ICC) was used to determine agreementof IOP values of one eye at each time point between visits.

 
Results:
 

Mean age of the patients was 59.15 ±11.12 yrs (45% females).Between-visit agreement of IOP values at each time point generallywas poor to fair, with ICCs ranging from 0.04 to 0.56. The correlationbetween visits was lowest at 7 am (0.04) and highest at 1pmand 7pm (0.56). Between-visit agreement of IOP change over timebetween time points was uniformly poor (ICCs -0.23 to 0.33).

 
Conclusions:
 

POAG patients do not manifest reproducible diurnal IOP patternwhen measured by Goldmann tonometry over a short time period.A single-day assessment of IOP is not adequate to evaluate adequacyof IOP control.  

  

 
Keywords: intraocular pressure • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • circadian rhythms 
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