Purchase this article with an account.
Yoon Jeon Kim, Jung Hwa Na, Youngrok Lee, Michael S. Kook; Association between Ocular Pulse Amplitude and Intraocular Pressure, Glaucoma severity, and Systemic Blood Pressure Variables measured during 24 hours in Normal-Tension Glaucoma. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3494.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To determine the association of ocular pulse amplitude (OPA) measured by dynamic contour tonometer (DCT) with glaucoma risk factors, visual field severity, and systemic blood pressure (BP) variables based on 24-hour collected data in normal-tension glaucoma (NTG).
One hundred and four patients with NTG were consecutively enrolled. All subjects underwent evaluation for glaucoma risk factors [age, gender, CCT, cup-to-disc (C/D) ratio, spherical equivalent(SE)], visual field parameters (MD, PSD), and 24-hour monitoring of intraocular pressure (IOP) measured by DCT and Goldmann applanation tonometry (GAT), OPA measured by DCT, and BP variables (Systolic BP, Diastolic BP, Mean arterial pressure, Arterial pulse pressure, Ocular perfusion pressure). Measurements of IOP, OPA, and BP were performed at two hour intervals. Both OPA and IOP by GAT and DCT were correlated with above predictor variables.
The average 24-hour OPA was positively associated with the average 24-hour IOP by DCT (p=0.003) and GAT (p=0.01), and arterial pulse pressure (p=0.002). However, it was not significantly associated with age, CCT, C/D ratio, SE, MD, PSD, and other BP variables. IOP measured by both GAT and DCT were positively correlated with the average 24-hour systolic BP (p<0.001), diastolic BP (p=0.003), and mean arterial pressure (p=0.001).
OPA was positively correlated with IOP and arterial pulse pressure. IOP was also positively associated with systemic BP based on 24-hour monitoring in NTG.
This PDF is available to Subscribers Only