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Julien Beynat, Anna Francoz, Frederic Nicot, Aurélie Cattanéo, Catherine P. Garcher, Alain M. Bron; Choroidal Thickness In Glaucomatous Eyes Measured By Spectral Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3497.
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The aim of our study was to evaluate and compare choroidal thickness (CT) of healthy subjects and glaucoma patients with spectral domain optical coherence tomography (SD-OCT) and to seek a correlation between CT and glaucoma severity.
Sixty-five healthy eyes, 16 eyes with early glaucoma , 13 eyes with moderate glaucoma and 24 eyes with advanced glaucoma were included in this cross-sectional study (one eye per patient). Retro-foveolar CT, foveolar retinal thickness and average retinal nerve fiber layer thickness (RNFL) were measured by SD-OCT. Humphrey 24-2 visual field was also performed. Spherical equivalent (SE) was measured with automatic refractometer.
Average retro-foveolar CT was statistically lower in glaucoma patients than in healthy subjects while the average retinal foveolar thickness was not statistically different between these two groups. The CT was not different according to glaucoma stage (p=0.725). We did not find any statistically significant correlation between CT and MD (p = 0.290), nor with CT and age (p=0.051), CT and retinal foveolar thickness (p=0,368), CT and RNFL thickness (p=0.777) and CT and SE (p=0.086).
This preliminary study showed that retro-foveolar CT measured by SD-OCT was significantly thinner in glaucomatous patients than in healthy subjects.
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