March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Change In logMAR Acuity Is Highly Correlated With Change In Certain Image Quality Metrics In Both Normal And Keratoconic Eyes
Author Affiliations & Notes
  • Ayeswarya Ravikumar
    College of Optometry, University of Houston, Houston, Texas
  • Edwin J. Sarver
    Sarver and Associates, Inc., Carbondale, Illinois
  • Raymond A. Applegate
    College of Optometry, University of Houston, Houston, Texas
  • Footnotes
    Commercial Relationships  Ayeswarya Ravikumar, None; Edwin J. Sarver, None; Raymond A. Applegate, University of Houston (P)
  • Footnotes
    Support  NIH/NEI R01 EY08520 (RAA), NIH/NEI R01 EY019105 (RAA), NIH/NEI P30 EY 07551 (Core Grant), Navy contract N0025910 P1354 (RAA), Borish Endowment (RAA)
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 3599. doi:https://doi.org/
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      Ayeswarya Ravikumar, Edwin J. Sarver, Raymond A. Applegate; Change In logMAR Acuity Is Highly Correlated With Change In Certain Image Quality Metrics In Both Normal And Keratoconic Eyes. Invest. Ophthalmol. Vis. Sci. 2012;53(14):3599. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine if change in logMAR visual acuity (VA) is highly correlated with change in key image quality (IQ) metrics in both normal and highly aberrated eyes.

Methods: : 15 normal, best corrected wavefront errors (WFEs) were randomly selected from the Thibos et al (J Opt Soc Amer A 19, 2329-48; 2002) 100 normal eye data set and 7 keratoconic (KC) WFEs from the Marsack et al data set (Optom Vis Sci 2007;84: 463-470). All WFEs were rescaled to a 4mm pupil. These 22 WFEs were scaled in magnitude up and down to yield 12 levels of WFE and in turn to calculate 30 IQ metrics. The wavefront error of 2 normal subjects was measured through their best corrections. For each subject, for each of the 264 WFEs, 3 unique acuity charts of 30% contrast were simulated after pre-compensating for the measured residual aberrations over a 3mm pupil, yielding 792 (22 * 12 * 3) unique logMAR chart simulations for each subject. For each chart, VA was measured on the 2 subjects up to the 5th letter missed through a 3mm pupil placed conjugate with the subject’s dilated pupil. VA was recorded as the change in VA (VA for test chart of interest - average VA obtained on 3 unaberrated charts). The resulting ΔVA was linearly regressed against change in each of the 30 IQ metrics in normal and KC eyes separately and in combination.

Conclusions: : Change in logMAR acuity is highly correlated (R2 greater than 0.75) with change in 3 log IQ metrics (neural strength, visual Strehl, light in the bucket) regardless of whether the eye is normal or highly aberrated supporting each IQ metric's role as a viable objective surrogate for visual acuity.

Keywords: visual acuity • aberrations • keratoconus 
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