March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Ocular Tolerance And Efficacy Of HeavySil 1500 As Endotamponade
Author Affiliations & Notes
  • Piero Fontana
    UO Oculistica, Ospedali Riuniti di Bergamo, Bergamo, Italy
  • Stefano Zenoni
    UO Oculistica, Ospedali Riuniti di Bergamo, Bergamo, Italy
  • Paolo Arpa
    Divisione Oculistica, Ospedale San Gerardo, Monza, Italy
  • Cesare Mariotti
    Clinica Oculistica, Universita Politecnica delle Marche, Ancona, Italy
  • Footnotes
    Commercial Relationships  Piero Fontana, None; Stefano Zenoni, None; Paolo Arpa, None; Cesare Mariotti, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 3771. doi:
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      Piero Fontana, Stefano Zenoni, Paolo Arpa, Cesare Mariotti; Ocular Tolerance And Efficacy Of HeavySil 1500 As Endotamponade. Invest. Ophthalmol. Vis. Sci. 2012;53(14):3771.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : heavySIL 1500 is a novel silicone oil for long-term endotamponade in vitreoretinal surgery. The compound is a medical sterile apyrogenic mixture of 75% high purity 5000 cSt silicone oil (polydimethylsiloxane) and 25% perfluoroalchiloxyde octane. This oil has the following properties: a density of 1,032 g/cm³ at 25ºC, a surface tension of 19 mN/m, a viscosity of 1500 cS and a refractive index of 1,3885. The substance is heavier than water and specifically intended to treat complex inferior retinal detachments. The aim of this study is to report our preliminary clinical data concerning its ocular tolerance and efficacy.

Methods: : in 24 eyes of 24 patients affected by complex inferior retinal detachment, after pars plana vitrectomy, endotamponade with heavySIL 1500 was maintained for a mean time of 64.9 days. Main outcome measures were: anatomical success, intraocular pressure (IOP) measurement, keratopathy, intraocular inflammation, oil emulsification and proliferative vitreoretinopathy (PVR) incidence.

Results: : at removal time, anatomical success was achieved with a single surgery in 21 patients (87.5%), with no report of IOP increase or keratopathy. Emulsification was observed in three cases (12.5%), mild transient inflammation in two patients (8.3%) and PVR developed in three patients (12.5%).

Conclusions: : our experience with heavySIL 1500 in selected cases of complex retinal detachment has been positive, with good efficacy and ocular tolerance.

Keywords: vitreous substitutes • vitreoretinal surgery • retinal detachment 

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