April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Efficacy Of Heating Wet Chamber Goggles( Blephasteam®) In Adult Blepharitis
Author Affiliations & Notes
  • Serge Doan
    Ophthalmology, Bichat Hospital and A de Rothschild Foundation, Paris, France
  • Frederic Chiambaretta
    Ophthalmology, Clermont Ferrand Hospital, Clermont Ferrand, France
  • Eric E. Gabison
    Hopital Bichat AP-HP Cornea, Fondation A de Rothschild, Paris, France
  • Isabelle Cochereau
    Ophthalmology, Bichat Hospital and A de Rothschild Foundation, Paris, France
  • Christophe Baudouin
    Ophthalmology, Quinze-Vingts Hospital, Paris, France
  • Footnotes
    Commercial Relationships  Serge Doan, Thea Laboratories (C); Frederic Chiambaretta, Thea Laboratories (C); Eric E. Gabison, None; Isabelle Cochereau, None; Christophe Baudouin, Thea Laboratories (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 3833. doi:
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      Serge Doan, Frederic Chiambaretta, Eric E. Gabison, Isabelle Cochereau, Christophe Baudouin; Efficacy Of Heating Wet Chamber Goggles( Blephasteam®) In Adult Blepharitis. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3833.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : Posterior blepharitis is a main cause of dry eye. Lid hygiene is an important treatment, but compliance is often poor because of its complexity and lack of specific devices. The aim of this study is to assess the efficacy of wet chamber warming goggles (Blephasteam®) in adult posterior blepharitis.

Methods: : In this interventional prospective uncontrolled study, adults with meibomian gland dysfunction were enrolled. Blephasteam® (Laboratoires Thea, Clermont-Ferrand, France) was used once or twice a day during 10 minutes, with a following lid massage. Main oucome measures were assessed at baseline and after 3 weeks, including symptoms, signs of blepharitis, Schirmer test, Break up time, corneal fluorescein vital staining, and tear osmolarity (measured with the Tearlab® system).

Results: : Eleven patients (8 women, 3 men), mean age 50 ± 16 years (24 to 70 years) were included at Bichat Hospital. After 3 weeks of treatment, mean global visual analogic scale symptom score and composite symptom score decreased by -18 mm (range, +32 to -57 mm on a 100 mm scale) and -4 points (range, +1 to -13 on a 18 points scale), respectively. Mean composite blepharitis score decreased by -3 points (range, +2 to -6 on a 20 points scale). No change was observed for the other parameters. Patient reported improvement was important in 6 cases, moderate in 2 and fair in 3.

Conclusions: : Blephasteam® wet chamber warming goggles are a promising alternative to classical lid hygiene techniques. A multicenter study is ongoing.

Clinical Trial: : http://www.clinicaltrials.gov NCT01091311

Keywords: cornea: tears/tear film/dry eye 

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