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Juliana E. Boneta, Karl E. Waite, Sanjeev Nath, Michael D. Bennett, Jerome Sherman; Peripheral Retinal Vascular Disorders Detected, Treated and Monitored with Optomap®FA as Compared to Spectralis® Fluorescein Angiography. Invest. Ophthalmol. Vis. Sci. 2011;52(14):4052.
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© ARVO (1962-2015); The Authors (2016-present)
To compare image quality and field of view obtained with both Optos FA and Spectralis FA in myriad peripheral retinal vascular disorders both pre and post treatment.
A retrospective review of 100 eyes of 50 patients with peripheral retinal vascular disorders who were imaged with both Optomap FA and Spectralis FA during the same clinical session at two facilities equipped with both technologies. Early phase angiography images were obtained with Spectralis FA then mid to late stage images were captured with the Optomap FA system. Far peripheral lesions imaged with Optos FA were then attempted to be imaged with Spectralis FA.The 50 patients included 5 with proliferative sickle cell retinopathy (PSR), 2 with coats disease, 2 with Lupus vasculopathy,1 with ROP, 1 with autosomal recessive hypercoagulopathy with temporal avascular zones, 2 eales disease with mid and far peripheral lesions,1 with peripheral phlebitis in MS, 1 with stage 4 IRVAN, 2 with "papillophlebitis" with peripheral vasculopathy in the "normal eye" and several with AV anastomosis. Also included were patients with peripheral findings in diabetic retinopathy, hypertensive retinopathy and various vein occlusions.
Both systems were able to obtain high quality images of perfused retina, zones of avascularity and areas of leakage in the posterior pole and extending to the equator.The Spectralis appeared to have an advantage in the posterior pole but identical, early phase images were not available with the optos for direct comparison.Optomap FA images documented significantly more lesions anterior to the equator in all 4 quadrants than did the Spectralis. This was especially true in PSR. Post treatment images of far peripheral lesions were also obtainable with Optos but far more difficult (if not impossible) to obtain with Spectralis.
Neither technology is ideal in all cases. Use of both in most disorders yields more clinically useful data than either alone. In disorders with peripheral pathology, such as PSR, Optos FA reveals more anterior lesions.
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