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Thierry Zeyen, Hans G. Lemij, Joseph Caprioli, Ingeborg Stalmans, David F. Garway-Heath; The European Glaucoma Optic Disc Appraisal study for Progression (EGODAP online study). Invest. Ophthalmol. Vis. Sci. 2011;52(14):4169.
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To determine the agreement and diagnostic accuracy of European non-specialized ophthalmologists to evaluate serial optic disc color stereo photographs for glaucomatous change. To assess if the agreement and diagnostic accuracy changed after a training session.
88 ophthalmologists from 15 European countries classified online 54 eyes with varying severity of glaucoma as stable or progressing based on the appraisal of serial optic disc stereo photographs. The reference standard was the 2/3 agreement of three glaucoma experts. Progression was classified as obvious or subtle by the experts. Four photo’s were presented twice. Intra- and inter-observer agreement were assessed using kappa statistics .The sensitivity and specificity were calculated per rater and compared before and after a training session using Wilcoxon signed-rank tests.
The intra- and inter-observer agreement (Κ) increased from 0.63 to 0.86 (P=0.013), and from 0.34 to 0.42 (P<0.0001) respectively after the training session. The sensitivity and specificity increased from 63.3% to 66.2% (P=0.021), and from 79.5% to 85.4% (P<0.001) respectively after the training session. The sensitivity in detecting obvious change increased from 78.4% to 86% (P<0.0001) after the training session.
The agreement and diagnostic accuracy of European non-specialized ophthalmologists in detecting glaucomatous progression by looking at serial optic disc stereo photos increased significantly after a training session.
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