April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Swelling of the Arcuate Retinal Nerve Fiber Layer after Internal Limiting Membrane Peeling for Idiopathic Macular Hole and Epiretinal Membrane Removal
Author Affiliations & Notes
  • Antonio P. Ciardella
    Ophthalmology, Policlinico S Orsola Malpighi, Bologna, Italy
  • Francesco Pichi
    Ophthalmology, Policlinico S Orsola Malpighi, Bologna, Italy
  • Mariachiara Morara
    Ophthalmology, Policlinico S Orsola Malpighi, Bologna, Italy
  • Chiara Veronese
    Ophthalmology, Policlinico S Orsola Malpighi, Bologna, Italy
  • Carlo Torrazza
    Ophthalmology, Policlinico S Orsola Malpighi, Bologna, Italy
  • Augustine Clark
    Ophthalmology, Policlinico S Orsola Malpighi, Bologna, Italy
  • Footnotes
    Commercial Relationships  Antonio P. Ciardella, None; Francesco Pichi, None; Mariachiara Morara, None; Chiara Veronese, None; Carlo Torrazza, None; Augustine Clark, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 4493. doi:
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      Antonio P. Ciardella, Francesco Pichi, Mariachiara Morara, Chiara Veronese, Carlo Torrazza, Augustine Clark; Swelling of the Arcuate Retinal Nerve Fiber Layer after Internal Limiting Membrane Peeling for Idiopathic Macular Hole and Epiretinal Membrane Removal. Invest. Ophthalmol. Vis. Sci. 2011;52(14):4493.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To report a particular appearance of the fundus, occasionally seen after removal of the internal limiting membrane (ILM).

 
Methods:
 

56 eyes of 56 consecutive patients with an epiretinal membrane and 38 eyes of 36 consecutive patients with idiopathic macular hole, who underwent pars plana vitrectomy and ILM peeling. All patients received a complete ophthalmic examination, infrared (IR) and autofluorescence (AF) photography, and SD-OCT preoperatively, at one week, and at one and three months post operatively. Vitrectomy and gas tamponade were performed with ILM peeling after staining with brilliant peel.

 
Results:
 

On IR and AF photographs, 13 (13.8%) of 94 eyes with ILM peeling exhibited the SAFL appearance one week to one month postoperatively. The SAFL appearance became more distinct during the first month after detection and disappeared after a mean period of two months. These features were best visualized by means of AF imaging, as three to five hypofluorescent striae originating from the optic nerve head, and running between the macula and the vascular arcades. SD-OCT scanning through the striae, indicated a swelling of the arcuate nerve fiber layer. No significant differences were found in eyes with or without SAFL for mean age or pre and postoperative BCVA (P>0.05 for all variables).

 
Conclusions:
 

The SAFL is an early transient appearance, not affecting visual recovery, which may be due to the same mechanical damage to Müller cells as previously described in DONFL. DONFL however, are reported at three months, as permanent lesions, located within the macular area, and with a ‘dimple’ appearance rather than swelling, on OCT.  

 
Keywords: vitreoretinal surgery • edema • nerve fiber layer 
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