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Hela Khlif, Hatem Zeghidi, Philippe Rapp; Interest Of The Biodegradable Collagen Matrix Implant In Surgical Excision Of Pterygium. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4027.
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Pterygium surgery required autograft to avoid recurrence.To evaluate the effectiveness and the safety of the biodegradable collagen matrix implant (iGen™) in pterygium surgery and the incidence of recurrence and post operative reactions.
This prospective study covers 15 cases of patients with primary pterygium, diagnosed at Max Fourestier Hospital.All patients had surgical excision of pterygium with conjunctival auto graft combined with IGen collagen Matrix implantation in subconjunctival space before suturing the conjunctiva.All surgeries were realized by the same surgeon.All patients were examined after surgery on D+1, D+15, D+1 month an then quarterly.Were analysed the inflammatory reaction, cicatrisation, status of recurrence and adverse events including sclerotitis and keratitis.
The mean follow-up was 18.4 months (range from 12 to 20 months).The iGen collagen Matrix was tolerated by all patients. No allergic reaction was reported.Autograft cicatrisation was obtained in one month postoperatively without inflammatory reaction. One case of keratisis is observed. No case of pterygium recurrence occurred.
Implantation of iGen collagen Matrix reduced contraction and promoted the formation of a nearly normal subconjunctival stroma. The use of this implant allows a lower recurrence rate and less inflammatory reaction and scar formation.
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