March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
A Hydrogel Corneal Inlay in Emmetropic Presbyopes: Unlocking Patient Satisfaction with Multivariate Statistical Methods
Author Affiliations & Notes
  • Adam J. Roy
    ReVision Optics, Lake Forest, California
  • Alan Lang
    ReVision Optics, Lake Forest, California
  • Guru Sharma
    ReVision Optics, Lake Forest, California
  • Tonya Porter
    ReVision Optics, Lake Forest, California
  • Keith Holliday
    ReVision Optics, Lake Forest, California
  • Arturo Chayet
    Codet Vision Institute, Tijuana, Mexico
  • Edna Favela
    ReVision Optics, Lake Forest, California
    Codet Vision Institute, Tijuana, Mexico
  • Enrique Barragan
    Laser Ocular Hidalgo, Monterrey, Mexico
  • Sandra Gomez
    Laser Ocular Hidalgo, Monterrey, Mexico
  • Footnotes
    Commercial Relationships  Adam J. Roy, Revision Optics (E); Alan Lang, ReVision Optics (E); Guru Sharma, ReVision Optics (E); Tonya Porter, ReVision Optics (E); Keith Holliday, ReVision Optics (E); Arturo Chayet, Revision Optics (C); Edna Favela, Revision Optics (E); Enrique Barragan, Revision Optics (C); Sandra Gomez, Revision Optics (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 4055. doi:
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      Adam J. Roy, Alan Lang, Guru Sharma, Tonya Porter, Keith Holliday, Arturo Chayet, Edna Favela, Enrique Barragan, Sandra Gomez; A Hydrogel Corneal Inlay in Emmetropic Presbyopes: Unlocking Patient Satisfaction with Multivariate Statistical Methods. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4055.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To build a multivariate statistical framework for formally determining postoperative drivers of patient satisfaction with the ReVision Optics® (RVO) intracorneal inlay*.

Methods: : Fifty-two emmetropic presbyopes were implanted with 2.0 mm diameter hydrogel intracorneal inlays in their non-dominant eyes. The Optec® 6500 Vision Tester was used to record uncorrected visual acuity (UCVA) in the treated eye. Self-evaluation was used to monitor visual symptoms, task performance, and satisfaction. A Visual Symptom Score summed the glare, halos, double vision, and fluctuation of vision records. Summing five questions each, for near and distance vision tasks, enabled two Task Performance Scores.

Results: : A regression framework was employed on a complete one, three, and six-month cohort (N=52) to isolate the relationships between clinical outcomes (covariates) and patient satisfaction (response). The first response was an indicator variable for satisfaction with near vision. After constructing a univariate logistic and estimating the one-month odds ratio, UCVA at Near, Near Task Performance Score, and Visual Symptom Score were all found to be strong (alpha level 0.05) postop drivers of near satisfaction. The next response was an indicator for distance vision satisfaction, and according to this univariate only Visual Symptom Score was strong (alpha level 0.05). Next a multivariate logistic was constructed that confirmed Near Task Performance Score is the strongest driver of near satisfaction, and for distance satisfaction, Visual Symptom Score was verified a stronger driver than UCVA at Distance. Distance Task Performance Scores had insufficient variation across patients to be included multivariately.

Conclusions: : Emmetropic presbyopes seek correction to improve near vision, and so the ability to perform near visual tasks is unsurprisingly the strongest driver of patient satisfaction at near. Near acuity has a variance on the same scale as measurement uncertainty, and therefore, may not be resolved multivariately. Distance vision in the treated eye has greater variation in acuity but remains less significant than visual symptoms in determining satisfaction with distance vision.CAUTION: Investigational device. Limited by Federal United States law to investigational use

Keywords: cornea: clinical science • presbyopia • refractive surgery 
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