Abstract
Purpose: :
To report the spectrum of iris lesions from a single ocular oncology center
Methods: :
Retrospective review of medical records
Results: :
3451 patients referred with an iris tumor. The mean age at presentation was 48 years (median 50 years, range 2 weeks to 95 years). There were 1423 males (41%) and 2028 females (59%). Of 3680 lesions, 2907 (79%) were benign and 773 (21%) were malignant, and 768 were cystic (21%) and 2912 (79%) solid. The lesions were located in the iris stroma (80%) or IPE (20%). The most common diagnostic categories within solid lesions were melanocytic (68%), non-melanocytic (11%), vascular (2%), metastasis (2%) and pseudotumors (5%). Specific diagnoses included nevus (41%), iris pigment epithelium (IPE) cyst (18%), melanoma (18%), freckle (3%), Lisch nodules (2%), melanocytoma (2%), melanocytosis (2%), and other (15%).
Conclusions: :
Of 3680 iris lesions, 79% were benign and the most common diagnosis included nevus (41%), IPE cyst (18%), melanoma (18%), and freckle (3%).
Keywords: tumors • iris • uvea