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Yuzhen Jiang, Paul J. Foster, David S. Friedman, Pak Sang Lee, Qiuxia Yin, Mingguang He; Association between Angle Width and Adult Anthropometric Parameters. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4471.
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To access the association of angle width with weight, height and body mass index in Chinese adults.
Adults aged 50 years and over were identified by clustered random sampling in a population-based survey in Liwan District, Guangzhou, southern China. Angle width was measured under static gonioscopy by Shaffer grade and number of quadrants in which pigmented trabecular meshwork was not visible. Weight and height were measured according to standard protocol. Body mass index (BMI) was calculated as weight (in kilograms) divided by the square of height (in meters). Angle occlusion was defined as pigmented trabecular meshwork not visible under static gonioscopy in at 3 quadrants (Definition1) or 2 quadrants (Definition2).
A total of 1358 subjects participated in the population-based survey. Anthropometric data were available for 912 subjects, who did not differ significantly in gender and refractive status but were relatively younger (P<0.05) as compared to the 446 subjects without weight and height data. The proportion of wide angle (mean Shaffer grade>/=3) increased in subjects with higher body weight and height; whereas the proportion of narrow angle (mean Shaffer grader</=1) decreased in subjects with higher body weight and height (P<0.001). Unvariate and multivariate analyses using logistic regression were constructed to evaluate the independent effects of height, weight and BMI on angle occlusion. In both univariate and multivariate analysis, BMI was the most important predictor for angle occlusion by both definitions. The association between weight and angle occlusion defined by both definitions was significant when adjusting for age and gender. Higher BMI and weight was independently associated with lower risk for angle occlusion, whereas the association between height and angle occlusion was no longer significant after adjusting for age, gender and axial length.
Higher BMI was an independent predictor of lower risk for angle occlusion. The association between height and angle width was eliminated after adjusting for age and gender.
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