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Kazuki Kuniyoshi, Hiroyuki Sakuramoto, Chota Matsumoto, Yoshikazu Shimomura; Relationship Between Oct Findings And Vision In Patients With Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4578.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the relationship between findings of spectral-domain optical coherence tomography (SD-OCT) and visual function in patients with retinitis pigmentosa (RP).
One-hundred and ninety-two eyes of 97 patients who were diagnosed as RP were examined and evaluated. The age of the patients ranged from 30 to 79. Funduscopy, visual acuity testing (VA), Goldmann perimetry (GP), full-field electroretinography (ERG), and SD-OCT were performed on all patients. Volume of the outer nuclear layer (ONL) was extrapolated based on the area of ONL in the vertical section of the macular area within 3-mm diameter in SD-OCT and compared with visual functions.
All RP-eyes in which IS/OS junction line remained beneath the fovea had VA better than 0.1. Fifty-five percent of the RP-eyes without IS/OS junction line had VA worth than 0.1. Eighty percent of the RP-eyes with the ONL area more than 0.3 mm2 on vertical 3mm-diameter section of the macula had VA better than 0.5. Sixty-four percent of the RP-eyes with the ONL area less than 0.2 mm2 on vertical 3mm-diameter section of the macula had VA worth than 0.1.
Presence of IS/OS junction line beneath the fovea is a sign that vision for daily-life can be kept for the patient, and the volume of ONL in foveal region reflects the level of visual acuity.
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