Abstract
Purpose: :
To describe the optical coherence tomography (OCT) characteristics of eyes with diabetic macular edema with the presence of vitreomacular interface abnormalities (VMIA).
Methods: :
This is a retrospective descriptive observational case series. Patients included had OCT (Zeiss Cirrus) macular scans done for suspected DME. Primary outcome measure was the presence of VMIA in an eye with macular thickening. Secondary outcome measures included presence or absence of epiretinal membrane (ERM) and partial posterior vitreous detachment (pPVD). Retinal thickening was identified by suprathreshold values in any of the nine macular subfields. Comparisons were made between DME and non-DME eyes.
Results: :
Results; 142 eyes of 71 patients were included. 69 eyes had DME by OCT criteria. 33/69 (47.8%) had VMIA with 21/69 (30.4) had pPVD and 15/69 (21.7%) had ERM, 3 eyes had both ERM and pPVD. There was trend to increase number of eyes with DRT, CME and SRF in the VMIA vs non VMIA group, (DRT 19/16, CME 25/23 and SRF 5/3).
Conclusions: :
Nearly 50% of the patients with DME had VMIA changes. Most had pPVD than ERM. Patients with VMIA tended to have more GRT, CME and SRF implying worse DME. As presence of VMIA can adversely effect resolution of DME, categorizing structural patterns apparent on OCT might allow a better choice of treatment options (surgical or chemical hyloidal separation) hence better visual outcomes.
Keywords: diabetic retinopathy • vitreous • macula/fovea