April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Influence Of Corneal Thickness On Biomechanical And Tomographic Parameters
Author Affiliations & Notes
  • Marcony R. Santhiago
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
  • Willian J. Dupps, Jr.
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
  • Steven E. Wilson
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
  • Footnotes
    Commercial Relationships  Marcony R. Santhiago, None; Willian J. Dupps, Jr., None; Steven E. Wilson, None
  • Footnotes
    Support  EY10056
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5192. doi:
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    • Get Citation

      Marcony R. Santhiago, Willian J. Dupps, Jr., Steven E. Wilson; Influence Of Corneal Thickness On Biomechanical And Tomographic Parameters. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5192.

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      © ARVO (1962-2015); The Authors (2016-present)

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To investigate differences between thin and thick corneas inbiomechanical and tomographic parameters


In this retrospective randomized clinical study, 62 eyes of62 refractive surgery patients who presented for screening wereenrolled.The main outcomes monitored were age, pre-operativespherical equivalent on manifest refraction (MRSE), ultrasonicpachymetry (USP), topographic parameters (keratometry values),biomechanical parameters (Corneal hysteresis [CH] and cornealresistance factor [CRF]) and tomographic parameters (cornealvolume [CV] and anterior chamber volume [ACV]). Eyes with aUSP thinner than 520 were included in the thin cornea group(22 eyes) and eyes with a USP thicker than 520 were includedin the thick cornea group (40 eyes).


The mean corneal thickness in the thin cornea group was 497.8± 14.7 µm and the mean corneal thickness in thethick cornea group was 561.7 ± 24.1 µm (p = 0.003).There were no significant differences in age, MRSE or mean keratometry.(p= 0.456, 0.657, 0.785 respectively). Tomographic values revealedno significant differences between the groups in CV (thin group57.9 ± 2.5 mm3 and thick group 61.3 ± 3.7 mm3p=0.121) and ACV (thin group 203.5 ± 25.5 mm3 and thickgroup 202.5 ± 33.9 mm3 p=0.872). The thin cornea grouphad significantly lower mean CH (8.9 ± 1.5 mmHg) andmean CRF 8.3 ± 1.9 mmHg compared to the thick corneagroup (CH 11.8 ± 2.0 mmHg [p= 0.034] and CRF 10.9 ±2.3 mmHg [p=0.021].


Corneal thickness does not significantly alter tomographic values.Thin corneas seem to have lower biomechanical values.Supportedby Research to Prevent Blindness, New York, NY  


Keywords: refractive surgery: other technologies • refractive surgery: corneal topography 

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