April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Influence Of Corneal Thickness On Biomechanical And Tomographic Parameters
Author Affiliations & Notes
  • Marcony R. Santhiago
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
  • Willian J. Dupps, Jr.
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
  • Steven E. Wilson
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
  • Footnotes
    Commercial Relationships  Marcony R. Santhiago, None; Willian J. Dupps, Jr., None; Steven E. Wilson, None
  • Footnotes
    Support  EY10056
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5192. doi:
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    • Get Citation

      Marcony R. Santhiago, Willian J. Dupps, Jr., Steven E. Wilson; Influence Of Corneal Thickness On Biomechanical And Tomographic Parameters. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5192.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract 
 
Purpose:
 

To investigate differences between thin and thick corneas inbiomechanical and tomographic parameters

 
Methods:
 

In this retrospective randomized clinical study, 62 eyes of62 refractive surgery patients who presented for screening wereenrolled.The main outcomes monitored were age, pre-operativespherical equivalent on manifest refraction (MRSE), ultrasonicpachymetry (USP), topographic parameters (keratometry values),biomechanical parameters (Corneal hysteresis [CH] and cornealresistance factor [CRF]) and tomographic parameters (cornealvolume [CV] and anterior chamber volume [ACV]). Eyes with aUSP thinner than 520 were included in the thin cornea group(22 eyes) and eyes with a USP thicker than 520 were includedin the thick cornea group (40 eyes).

 
Results:
 

The mean corneal thickness in the thin cornea group was 497.8± 14.7 µm and the mean corneal thickness in thethick cornea group was 561.7 ± 24.1 µm (p = 0.003).There were no significant differences in age, MRSE or mean keratometry.(p= 0.456, 0.657, 0.785 respectively). Tomographic values revealedno significant differences between the groups in CV (thin group57.9 ± 2.5 mm3 and thick group 61.3 ± 3.7 mm3p=0.121) and ACV (thin group 203.5 ± 25.5 mm3 and thickgroup 202.5 ± 33.9 mm3 p=0.872). The thin cornea grouphad significantly lower mean CH (8.9 ± 1.5 mmHg) andmean CRF 8.3 ± 1.9 mmHg compared to the thick corneagroup (CH 11.8 ± 2.0 mmHg [p= 0.034] and CRF 10.9 ±2.3 mmHg [p=0.021].

 
Conclusions:
 

Corneal thickness does not significantly alter tomographic values.Thin corneas seem to have lower biomechanical values.Supportedby Research to Prevent Blindness, New York, NY  

 

 
Keywords: refractive surgery: other technologies • refractive surgery: corneal topography 
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