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Anja Kissner, Frederik Raiskup, Eberhard Spoerl, Lutz E. Pillunat; Long-term Results Of Corneal Collagen Cross-linking In Post-lasik Keratectasia. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5196.
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To evaluate the long-term corneal stability after corneal collagen cross-linking with riboflavin and UVA in eyes with LASIK-induced keratectasia.
At the first and all follow-up examinations refraction, best corrected visual acuity and corneal topography were recorded. 10 eyes of 6 patients were analyzed up to 8 years. Every single case was evaluated concerning stability or progression.
Mean follow-op was 5.8 ± 1.7 years, mean age was 34.9 ± 3.8 years. 5 patients (8 eyes) were female, one patient (2 eyes) was male. The difference between baseline and last follow-up of mean Kapex was -0.92 ± 3.46 D. In 6 eyes the findings of K-values remained stable or even partially decreased. In 4 eyes of 2 patients K-values progressed despite of the procedure and these were patients with additional risk factors for progression as neurodermitis, allergy or pre-existing keratoconus.
Corneal collagen cross-linking seems to be similar as in cases of keratoconus a therapeutic option to halt progression of post-LASIK iatrogenic keratectasia. We should be aware of patients with additional risk factors and in counseling inform them about possibility of further progression despite of CXL procedure, necessity of frequent follow-up and eventual retreatment.
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