April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Safety And Efficacy Of Crosslinking Following Intacs Implantation For The Stabilization Of Keratoconus
Author Affiliations & Notes
  • Silas L. Wang
    Department of Ophthalmology, New York University, New York, New York
  • Anastasios J. Kanellopoulos
    Department of Ophthalmology, New York University, New York, New York
    Laservision.gr Institute, Athens, Greece
  • Footnotes
    Commercial Relationships  Silas L. Wang, None; Anastasios J. Kanellopoulos, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5200. doi:
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    • Get Citation

      Silas L. Wang, Anastasios J. Kanellopoulos; Safety And Efficacy Of Crosslinking Following Intacs Implantation For The Stabilization Of Keratoconus. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5200.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the safety and efficacy of ultraviolet A (UVA) induced collagen crosslinking (CXL) performed following Intacs implantation for keratoconus (KCN).

Methods: : 12 KCN cases that had undergone Intacs corneal implants 6 to 32 months previously were treated with CXL. Pre-operative evaluation included uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refractive error, keratometry (K), pachymetry (P), endothelial cell count (ECC), and corneal topography (T). Following PTK (50 microns, 6.5mm diameter), the eyes underwent UVA-induced CXL after the administration of 0.1% riboflavin drops.

Results: : The mean follow-up was 1.6 years (range 1-4 years). The mean pre-operative and post-operative values were respectively: UCVA: 0.3, 0.4; BSCVA: 0.4, 0.5; spherical equivalent: -2.25 D, -2.00 D; mean keratometry: 45.5 D, 44.5 D; total pachymetry: 445, 425; endothelial cell count: 2750, 2700. None of the cases developed signs of ectasia progression within the follow-up period.

Conclusions: : CXL appears to be a safe and effective adjunctive treatment in preventing ectasia in eyes that had previously had Intacs implantation.

Keywords: keratoconus • refractive surgery: other technologies 
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