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Silas L. Wang, Anastasios J. Kanellopoulos; Safety And Efficacy Of Crosslinking Following Intacs Implantation For The Stabilization Of Keratoconus. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5200.
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To evaluate the safety and efficacy of ultraviolet A (UVA) induced collagen crosslinking (CXL) performed following Intacs implantation for keratoconus (KCN).
12 KCN cases that had undergone Intacs corneal implants 6 to 32 months previously were treated with CXL. Pre-operative evaluation included uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refractive error, keratometry (K), pachymetry (P), endothelial cell count (ECC), and corneal topography (T). Following PTK (50 microns, 6.5mm diameter), the eyes underwent UVA-induced CXL after the administration of 0.1% riboflavin drops.
The mean follow-up was 1.6 years (range 1-4 years). The mean pre-operative and post-operative values were respectively: UCVA: 0.3, 0.4; BSCVA: 0.4, 0.5; spherical equivalent: -2.25 D, -2.00 D; mean keratometry: 45.5 D, 44.5 D; total pachymetry: 445, 425; endothelial cell count: 2750, 2700. None of the cases developed signs of ectasia progression within the follow-up period.
CXL appears to be a safe and effective adjunctive treatment in preventing ectasia in eyes that had previously had Intacs implantation.
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