April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
A Confocal Microscopy Analysis Of The Stromal Corneal Nerves In Keratoconus Patients
Author Affiliations & Notes
  • Manuel Ramirez
    Cornea, Asoc Para Evitar la Ceguera, Mexico City, Mexico
  • German Villagomez
    Cornea, Asoc Para Evitar la Ceguera, Mexico City, Mexico
  • Everardo Hernandez-Quintela
    Cornea, Asoc Para Evitar la Ceguera, Mexico City, Mexico
  • Ramon Naranjo-Tackman
    Cornea, Asoc Para Evitar la Ceguera, Mexico City, Mexico
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5216. doi:
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      Manuel Ramirez, German Villagomez, Everardo Hernandez-Quintela, Ramon Naranjo-Tackman; A Confocal Microscopy Analysis Of The Stromal Corneal Nerves In Keratoconus Patients. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5216.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the stromal corneal nerves morphology and thickness in keratoconus patients.

Methods: : 25 eyes of 20 keratoconus patients were examined with the confocal microscope (Confoscan 4, Fortune Technologies, Italy), a central scan of the total corneal thickness was taken in every exam. Corneal stromal nerves morphology and thickness were evaluated by using the Navis V. 3.5.0. Software (NIDEK, Multi-Instrument Diagnostic System, Japan). Nerve thickness was obtained from the mean between the widest and the narrowest portion of each stromal nerve.

Results: : Corneal stromal nerves were observed as irregular linear hiper-reflective structures with widest and narrowest portions. Mean corneal stromal nerves thickness was 6.9 ± 2.0 microns, range from 3.5 to 12.0 microns.

Conclusions: : It is possible to evaluate corneal stromal nerves morphology and thickness by using confocal microscopy in vivo in keratoconus patients.

Keywords: keratoconus • imaging/image analysis: non-clinical • nerve fiber layer 
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