April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Rate of Disinfection of Various Multi-Purpose Solutions and a Hydrogen Peroxide Solution Against Clinically Relevant Bacterial and Fungal Species
Author Affiliations & Notes
  • Patricia A. Walsh
    Microbiology, Bausch + Lomb, Rochester, New York
  • Brien C. David
    Microbiology, Bausch + Lomb, Rochester, New York
  • Deborah McGrath
    Microbiology, Bausch + Lomb, Rochester, New York
  • Denise Callahan
    Microbiology, Bausch + Lomb, Rochester, New York
  • Juliann M. Mason
    Microbiology, Bausch + Lomb, Rochester, New York
  • Sue Norton
    Microbiology, Bausch + Lomb, Rochester, New York
  • Footnotes
    Commercial Relationships  Patricia A. Walsh, Bausch + Lomb (E); Brien C. David, Bausch + Lomb (E); Deborah McGrath, Bausch + Lomb (E); Denise Callahan, Bausch + Lomb (E); Juliann M. Mason, Bausch + Lomb (E); Sue Norton, Bausch + Lomb (E)
  • Footnotes
    Support  Bausch + Lomb
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5846. doi:
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      Patricia A. Walsh, Brien C. David, Deborah McGrath, Denise Callahan, Juliann M. Mason, Sue Norton; Rate of Disinfection of Various Multi-Purpose Solutions and a Hydrogen Peroxide Solution Against Clinically Relevant Bacterial and Fungal Species. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5846.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Evaluating the disinfection efficacy of five Multi-Purpose Solutions (MPS) and a Hydrogen Peroxide Solution (H2O2) against clinically relevant microorganisms at reduced exposure times.

Methods: : Using a modification of the ISO 14729 standard, the disinfection efficacy of several MPS and H2O2 were evaluated against clinically relevant bacteria (methicillin-resistant Staphylococcus aureus, Haemophilus influenzae, and Streptococcus pneumoniae) and clinically relevant fungi (Fusarium solani, Fusarium oxysporum and Candida albicans) at reduced exposure times.

Results: : The ISO 14729 primary acceptance criterion was used as a reference for interpretation of the results. Each solution showed a time dependency for disinfection efficacy, some greater than others over the time points measured in this study. Disinfection efficacy for some solutions increased with exposure time, measured from 10 through 60 minutes, while for others there seemed to be less effect. Additionally, these organisms showed different susceptibilities to the various MPS and H2O2.

Conclusions: : This study indicates that the rate of disinfection of a given lens care disinfection solution varies depending on the challenge organism. For some solutions, the disinfection efficacy improved when exposure times were increased from 10 minutes through 60 minutes exposure, while for others, there seemed to be less improvement in efficacy during the exposure times measured in this study. The results do not suggest a benefit for reducing the current disinfection regimen recommended by the manufacturer’s instructions.

Keywords: contact lens • bacterial disease • fungal disease 
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